Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"mCAT-1"”.
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The Role of Adaptor Protein Grb2 in Ecotropic Retrovirus Entry and Receptor Trafficking
… is the mouse cationic amino acid transporter 1 (mCAT1). Using a siRNA screen to detect host cell components important for virus infection, we identified growth factor receptor-bound protein 2 (Grb2), as a key protein for eMLV infection. Grb2 is an adaptor that has been shown to couple cell …
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Making In Utero Gene Therapy Safer and More Efficient: A First Step Towards Clinical Realization
… murine cationic amino acid transporter type 1 (mCAT-1) receptor gene which is found only in mouse and rat. The murine stem cell virus (MSCV) γ-retroviral vector (MR4IN) acts as the second delivery-vehicle, which carries the therapeutic protein and is packaged with the murine ecotropic envelope …