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Showing 1 to 1 of 1 for “"mAb disposition"”.
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Modeling approaches to characterize the disposition of monoclonal antibodies
Monoclonal antibodies (mAbs) are engineered immunoglobulins G (IgG) used for more than 20 years as targeted therapy in oncology, infectious diseases and (auto-)immune disorders. Their protein nature greatly influences their pharmacokinetics (PK), presenting typical linear and non-linear behaviors. …