Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"m6A methylation"”.
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Effects of m6A DNA methylation by bacterial methyltransferase in colorectal cancer
<p>Effects of m6A DNA methylation by bacterial methyltransferase in colorectal cancer Fabian Alejandro Mendoza Galvan Advisory Professor: Angela H. Ting, Ph.D. Fusobacterium nucleatum animalis (Fna) is found in the human oral cavity and gut. A distinct clade of Fna is primarily enriched in the …
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Epitranscriptional Control of the Caspase-2—MDM2—p53 Axis: The Role of the m6A Writer in p53 Signaling.
… an unexpected role for N6-methyladenosine (m6A) RNA methylation as an essential post-transcriptional determinant of p53 activation in response to centrosome-derived stress. Using a genome-wide CRISPR/Cas9 screen coupled with a fluorescent reporter system, we uncovered all seven components of …
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Investigations into the role of RNA modification in the function of the c-Myc IRES
… the cytoplasm and recent data have shown that m6A methylation alone, which occurs in the nucleus, is sufficient to promote internal ribosome entry. Therefore, a testable hypothesised is that the “nuclear” event required for IRES function is RNA modification. Prior data from a yeast 3 Hybrid …