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Showing 1 to 2 of 2 for “"m-calpain"”.

  1. The role of proteases in development of cancer in mice

    … a modified fluorescent assay, differences in m-calpain and calpastatin activity were found between seven and nine month ethyl carbamate treated mice. The calpain to calpastatin ratio is higher in the nine month treated mice due to a decline in the activity of calpastatin with age. Changes in the …

    lincoln Repository record for The role of proteases in development of cancer in mice (opens in a new tab)

  2. Synthesis of Novel Sulfonamide-Based Calpain Inhibitors and Their Potential as Anti-Tumor Agents

    <p>Calpain is a class of intracellular cytoplasmic cysteine proteases.1 The enzyme participates in different intracellular signaling pathways that are mediated by Ca2+.2 The two major isoforms of calpain universally distributed in most mammalian tissues are calpain 1 (µ-calpain) and calpain 2 …

    tenn-hsc Repository record for Synthesis of Novel Sulfonamide-Based Calpain Inhibitors and Their Potential as Anti-Tumor Agents (opens in a new tab)