Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"lysosomal membrane permeabilization"”.
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Differential Autophagic Responses to Nano-Sized Materials
… titanium dioxide nanoparticles, however, induced lysosomal membrane permeabilization, leading to blockage of autophagic flux and accumulation of autophagic substrates. These results point to the complexity of the autophagic response to nanomaterials, which may involve activation of the …
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In vitro investigation of the anticancer activity and molecular mechanisms of action of albumin nano-encapsulated copper/zinc diethyldithiocarbamate in human pancreatic cancer cells
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers, with a 5-year survival rate of 12%, and is projected to become the second leading cause of cancer-related mortality by 2030. Chemotherapy remains the main treatment option but offers limited benefits due to toxicity and …