Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 356 for “"lymphoid"”.
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Group 2 innate lymphoid cells and reproduction
… findings showed that tissue-resident innate lymphoid cells (ILCs) are crucial regulators of both physiology and pathology of the tissues they populate. Uterine natural killer (uNK) cells are a subtype of ILCs known to regulate trophoblast invasion, uterine vascular adaptation to pregnancy, …
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Lymphocyte subset variability between human lymphoid tissues
Most adaptive immune lymphocytes are in the lymphoid tissues. However, studies of human lymphocytes to date have primarily investigated cells from the blood, and lymphoid tissues remain poorly studied. This thesis explores the hypothesis that there is local variation of B cell subsets between the …
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Fibroblast Regional Identity in the Murine Lymphoid System
… study fibroblast heterogeneity within the murine lymphoid system was investigated by analysing gene and protein expression. Fibroblasts were isolated from a range of lymphoid and peripheral sites. Our findings show that fibroblasts grown from different sites show heterogeneous gene and protein …
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Imaging innate immune cell behaviour in lymphoid organs
… tissues for pathogen killing. Type 2 innate lymphoid cells (ILC2s) mediate early responses to helminths and allergens via cytokine production. Innate immune cells interact with adaptive immune cells, for example via major histocompatibility complex class II (MHCII) expression for antigen …
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Nasal Associated Lymphoid Tissue in health, infection and autoimmunity
… specific B cells takes place in specialised lymphoid tissues. Much of what we know about this process is inferred from mouse models and studies of human peripheral blood. Both approaches have limitations, through either the inter-species variations of mouse models, or the local tissue immune …
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Compartmentalization of HIV-1 in the Secondary Lymphoid Tissues
Follicular dendritic cells (FDCs) reside in the lymphoid follicles of the secondary lymphoid tissues (sLTs). Following the infection of an individual with human immunodeficiency virus type 1 (HIV-1), viral particles are trapped in massive quantities on the surfaces of FDCs. HIV-1 viral compartments …
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Reciprocal Relationships Between the Neuroendocrine System and Lymphoid Cells
… of glucocorticoids and cathecholamines. Lymphoid cells possess receptors for both of these stress-related hormones, and activation of these receptors affects functional activities of lymphoid cells. In the present experiments, it is demonstrated that activation of porcine splenocytes with …
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Innate Lymphoid Cell Diversity in Pregnancy and Ovarian Cancer
… suppression and reduced cytotoxicity. Innate Lymphoid Cells (ILCs) are a diverse group of lymphocytes which exhibit tissue specific phenotypes and functions. They are found in both the uterine lining during early pregnancy (decidua) and the ascites of ovarian cancer patients. Despite several …
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THE EFFECTS OF ACIDOSIS ON SURVIVAL PATHWAYS IN LYMPHOID MALIGNANCIES
Intensive research in the field has revealed that, within tumors, cancer cells must grow and develop amidst an increasingly complex and demanding background. Cancer cells acquire the ability to recognize and respond to numerous features of this tumor microenvironment, generating a …
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Effect of Fowlpox Virus on Lymphoid Tissues of the Chicken
Made available in DSpace on 2014-12-09T22:30:07Z (GMT). No. of bitstreams: 1 6604251.pdf: 5823842 bytes, checksum: 5b7b24a87b306e463b62be142d821cd8 (MD5) Previous issue date: 1965
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Antigen-specific memory T cell distribution in non-lymphoid tissue
… airways have been cleared and restored. Although lymphoid-appearing nodules were detected in the lungs 31 dpi, no clusters of B cells and T cells suggesting induced BALT were identified by immunofluorescence.
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Molecular definition of group 1 innate lymphoid cells in the uterus
Uterine NK cells (uNKs) are group 1 (g1) innate lymphoid cells (ILCs) that have been shown to regulate remodelling of uterine blood vessels, an event necessary to support fetal growth. Recently, other ILCs were identified in the mucosa and wall of the uterus of mice and women, pregnant or not. They …
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The role of NF-kB2 in secondary and tertiary lymphoid tissue development
… pathway in the development of secondary lymphoid organs (SLOs) has been well described. Tertiary lymphoid organs (TLOs) include intestinal cryptopatches (CPs) and isolated lymphoid follicles (ILFs). This thesis investigates the role of the alternative NF-\(\kappa\)B pathway in the …
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Studies on Lymphoid Responsiveness to Plasmodium Berghei in the A/j Mouse
Made available in DSpace on 2014-12-14T16:11:18Z (GMT). No. of bitstreams: 1 7915368.pdf: 4435662 bytes, checksum: f9481dc4b28e11a35eeddbcc310b46ab (MD5) Previous issue date: 1979
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Immune Checkpoint Molecule Expression in Canine Lymphoma and Canine Reactive Lymphoid Hyperplasia
… ligands PD-L1 and PD-L2 in lymphoma and reactive lymphoid hyperplasia controls. Methods: Retrospective: formalin-fixed paraffin-embedded (FFPE) tissue from dogs with untreated lymphoma (n=10) and reactive lymphoid hyperplasia (n=10). Prospective: fine-needle aspirates (FNAs) from dogs with …
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Innate Lymphoid Cell Characterization and Ilc2S In Neuroinflammation In Aging and Sex Differences
… prefer Th2 responses. As tissue-resident innate lymphoid cells (ILC) are novel immune cells that are the innate complement to T cells, understanding their role in aging and sex differences is imperative.</p> <p>Here, ILCs are characterized within various C57Bl6/J mice tissues and defined cytokine …
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Persistant GATA2 Expression Promotes Self-Renewal of Myeloid Progenitors and Blocks Lymphoid Differentiation.
… Granulocyte Monocyte Progenitor (GMP) and the lymphoid block occurs after the Common Lymphoid Progenitor (CLP) in transgenic mice. Finally using the C352P mutant we showed that myeloid expansion and B lymphoid block require DNA binding activity of GATA2-ERT and were not due to the dominant …
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