Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 838 for “"lymphocytes"”.
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Stochastic regulation of signaling in lymphocytes
… specific immune responses. The orchestrators are lymphocytes, including B cells and T cells. When lymphocytes are stimulated strongly enough by infected or antigen-presenting cells, the signal will be transmitted through a complex network of biochemical reactions underlying the cellular functions. …
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Characterization of a Novel Receptor CS1 in Human Lymphocytes; Studies in Natural Killer Cells and B-Lymphocytes
… was to investigate the roles of CS1 on human lymphocytes. The molecular and functional characterization of CS1 receptor in the natural killer (NK) cells and B lymphocytes was investigated. CS1 (CRACC, novel Ly9) is a novel member of the CD2 family receptor expressed on natural killer (NK), T …
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B and T Lymphocytes in Human Pregnancy
… this purported depression was due to fewer T-lymphocytes or a dysfunction of these cells. T cells were measured by the rosette technique using neuraminidase treated sheep red blood cells (SRBC). B cells were measured using a SRBC-hemolysin-guinea pig complement indicator system. The total …
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Biophysical responses of lymphocytes to environmental stress
… immediately after growth factor depletion in lymphocytes promote adaptation to reduced nutrient uptake. We describe an acute biophysical response to growth factor withdrawal, characterized by a simultaneous decrease in cell volume and increase in cell density prior to autophagy initiation, …
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Telomere and Telomerase Dynamics in Human T Lymphocytes
Advanced cancer is characterized by a phenotype that permits cells to divide indefinitely while cellular aging is characterized by cells ceasing to divide. It is believed that senescence may have evolved as an anti-cancer protection mechanism in long-lived species such as humans. Therefore, cancer …
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Biological effects of trogocytosis on CD4+ T lymphocytes
<p>Antigen recognition by CD4+ T cells leads to large-scale spatial and temporal molecular redistributions, forming the immunological synapse. We have previously shown that upon dissociation, T cells capture large membrane fragments from antigen-presenting cells directly from the immunological …
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Biological effects of trogocytosis on CD4+ T lymphocytes
<p>Antigen recognition by CD4+ T cells leads to large-scale spatial and temporal molecular redistributions, forming the immunological synapse. We have previously shown that upon dissociation, T cells capture large membrane fragments from antigen-presenting cells directly from the immunological …
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Modulation of T Lymphocytes by Tumor-Released Survivin
… Of primary interest are tumor-infiltrating T lymphocytes, which have been shown to have a key role in modifying the dynamics of the tumor microenvironment to promote or prevent tumor growth. While there is much in vitro and in vivo evidence for a modification of the tumor infiltrating T cell …
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Investigating the antibody-independent functions of B lymphocytes
B cells are critical for the generation of antibody, but there is increasing evidence that they have a broader functional remit: For example, innate B1a cells are a critical source of granulocyte macrophage colony-stimulating factor (GM-CSF) during Gram-negative sepsis, inducing neutrophil …
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Activation and Maintenance of Intestinal Intraepithelial Lymphocytes (IELs)
… the IECs that have been named intraepithelial lymphocytes (IELs). As the main lymphoid population within the intestinal barrier, IELs are thought to have an important role in intestinal homeostasis maintenance, as well as a role in intestinal inflammatory and autoimmune diseases such as …
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The Functions of Autophagy Genes in Lymphocytes and Osteoclasts
… mice lacking essential autophagy genes in B lymphocytes, T lymphocytes, and osteoclasts. We found that the essential autophagy gene <italic>Atg5</italic> was important for B cell development and for the maintenance of B-1a B cell numbers but not peripheral B-2 B cell numbers. In T cells, …
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Intrinsic genetic resistance of lymphocytes to influenza virus infection
… I alleles may be associated with protection of lymphocytes against infection by influenza virus. There was absence of viral transcription in the lymphocytes of HLA-A homozygous subjects, although all monocytes were infected.\r\nMy specific aim was to determine if such resistance was evident in …
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