Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"lymphatic metastasis"”.
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Dissecting cell-autonomous and microenvironmental factors governing lymphatic metastasis in breast cancer
Metastasis is the primary cause of deaths in cancer patients. Tumour dissemination can occur through the bloodstream or lymphatic system. The presence of tumour cells in the draining lymph node (lymph node involvement) represents the most important prognostic factor for breast cancer patients. …
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Identification and Characterization of Determinants of Head and Neck Tumor Cell Invasion
… majority of patients die from local invasion or lymphatic metastasis. The mechanism(s) underlining the invasiveness of HNSCC are poorly understood. Utilizing a panel of HNSCC cell lines previously established in our laboratory, we tested the application and relevance of the three-step hypothesis …
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Lymphatic pathophysiology of tumors
… on cancer survival, but the mechanisms for lymphatic metastasis are not well understood. The universal finding in solid tumors of an absence of functional lymphatic vessels seems paradoxical, as cancer cells do travel through lymphatics in order to disseminate. In order to address some of …
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An Ultra-pH-Sensitive Logic Decodes Cancer Imaging and Immunotherapy
Pages 186-213 are misnumbered as pages 219-246.
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TLR4 is a novel determinant of the response to paclitaxel in breast cancer
… tumors often correlates with chemoresistance and metastasis. Despite these logical considerations implicating, TLR4 in chemoresistance and metastasis, limited evidence is available to support this claim experimentally. Most of the previous studies had used LPS, to show a tumor-promoting role of …
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CELLULAR MRI: TRACKING THE MIGRATION OF METASTATIC CANCER CELLS IN THE LYMPHATIC SYSTEM
The role of the lymphatics as a mode of tumor cell transport has been known for some time, and remains of critical importance since a majority of cancer deaths result from metastatic dissemination away from the primary tumor. In the studies performed in this thesis novel cellular MRI technology and …