Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 277 for “"lymph nodes"”.
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Stromal components and the control of lymphocyte trafficking in human lymph nodes
Lymph nodes (LNs) are located at the interface between the blood and lymphatic systems, enabling the presentation of tissue-derived antigen to blood-derived lymphocytes. Understanding immune responses in human LNs requires better knowledge of the stromal cells and structural components of the LN …
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Interrogating the functional adaptions of Tumour-draining lymph nodes (TDLNs) and the subsequent impact of checkpoint inhibition
Lymph nodes (LNs) function as immunological hubs whereby antigen and naïve lymphocytes meet to facilitate an immune response. In cancers, the tumour-draining lymph node (TDLN) is where the initial anti-tumour immune response occurs. Previous studies have demonstrated that TDLNs undergo dramatic …
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Computed Tomographic Studies of Characteristics of Selected Canine Lymph Nodes Relevant to Staging and Treatment of Solid Tumours
… of this body of research were to describe the lymphatic drainage of the canine pelvic limb, characteristics of normal popliteal lymph nodes, and the location and CT characteristics of presumed normal medial iliac lymph nodes.
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Comparison of two different methods to detect telomerase activity in normal and neoplastic lymph nodes in the dog
One of the several differences between a normal and a neoplastic cell is that there is a phisiological limit to the number of possible cell replications in the former, whereas it appears to be unlimited in the latter. For this reason, cancer cells are thought to undergo a phenomenon of …
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Computer-Aided Detection of Pathologically Enlarged Lymph Nodes On Non-Contrast Ct In Cervical Cancer Patients For Low-Resource Settings
… metastasis outside of the field and/or to boost lymph nodes in the abdomen and pelvis. The first goal of this project was to create a program which automatically identifies positive cervical cancer lymph nodes on non-contrast daily CT images, which are widely available in LMICs(1).</p> <p>A …
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Interactions of Mast Cells with the Lymphatic System: Delivery of Peripheral Signals to Lymph Nodes by Mast Cell-Derived Particles
… have been shown to enhance the number of naive lymphocytes in infection site-draining lymph nodes, and to encourage the migration of dendritic cells to responding lymph nodes.</p><p>Although infections usually occur at peripheral sites, adaptive immune responses are initiated in distant lymph …
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Diffusion Weighted MR Imaging in the Differentiation between Metastatic and Benign Lymph Nodes in Canine Patients with Head and Neck Disease
In dogs with large primary tumors, regional lymph node involvement or evidence of distant metastasis can have worse prognoses and significantly decreased survival. Lymph node size alone has been shown to be insufficient as a predictor for the accurate clinical staging of some canine neoplasia, …
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Pulsed-field gel electrophoresis subtyping of salmonella isolates from carcasses, lymph nodes and fecal samples of cattle from slaughter facilities in Mexico
… addition, 33 confirmed Salmonella isolates from lymph nodes (mandibular, mediastinal, and mesenteric) and feces from cattle of one slaughter facility of Merida, Mexico were molecularly characterized by PFGE. High concordance (88.4%) was found between serotype and PFGE banding subtype; Salmonella …
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Lymph Nodes in Maxillofacial Surgery – In the Norm and Most Common Diseases // Лимфни възли в лицево-челюстната хирургия – в норма и най-чести заболявания
This thesis examines lymph nodes in the maxillofacial region, focusing on their anatomy, physiological function, and pathological changes in common diseases. A comprehensive analysis of patients with lymph node diseases of the head and neck, hospitalised and treated at the Clinic of Maxillofacial …
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Ex vivo proton magnetic resonance spectroscopy (1HMRS) of normal, reactive and malignant canine lymph nodes: evaluation of the choline metabolite as a marker for malignancy
… of the choline metabolite in canine lymph nodes ex vivo, and compare choline ii levels (via choline signal-to-noise ratio or Cho SNR) among populations of normal, reactive, and malignant lymph nodes. Our hypothesis was that choline would be detectable in canine lymph nodes ex vivo, …
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Lymph node and peri-lymph node stroma : phenotype and interaction with T-cells
… located inside and surrounding skin-draining lymph nodes play a key role in regulating immune responses. We studied distinct populations of lymph node stromal cells from both human subjects and animal models in order to describe their phenotype and function. In the mouse model, we studied two …
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T cell Immunomodulation in the Lymph Node for Inhibition of Load-Induced Osteoarthritis
… the crosstalk of joint pathology with local lymph nodes in OA is poorly understood. We characterized the T cell immune response in local lymph nodes following the in vivo mechanical loading of joints. First, we analyzed the change in T cells in lymph nodes following load-induced OA using flow …
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Synergistic development of an engineered biodegradable theranostic probe and lymph node organ-on-a-chip to study nanoparticle-lymphatic interactions
The lymphatic system plays a vital role in controlling immune response. Despite this, cancer often reshapes the lymphatic microenvironment and metastasizes into lymph nodes. Theranostic (therapeutic + diagnostic) nanoparticles have been used in a variety of applications, including the detection and …
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The pathology of tuberculosis, caused by mycobacterium tuberculosis, in a herd of semi free-ranging springbok (Antidorcas marsupialis)
… lesions in the lungs, pleura and respiratory lymph nodes. Limited sampling was done but microscopic tuberculosis lesions were found in almost all the organs sampled, and acid-fast bacilli were generally numerous. Six healthy rams were culled nine months later and a pilot study indicated …
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TREM-2 and Dendritic Cells in the Pathogenesis of Allergic Airway Inflammation
… capturing inhaled antigens and migrating to the lymph nodes to mediate T-helper cell responses. Lung DCs consist of a heterogenous population of cells that express CD11c and are further divided into two major subsets based on the expression of CD11b and CD103. Both subsets have been shown to …
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Finding Typhoid Mary: Identifying Latent Carriers of Salmonella enterica serovar Typhimurium
… aceA expression could be detected in cattle lymph node samples. Supra-mammary lymph nodes from 40 dairy cattle and mesenteric lymph nodes from 100 culled cattle were sampled and submitted for culture and qPCR. None of the supra-mammary lymph nodes were positive for Salmonella via culture or …
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Understanding the Role of Dendritic Cell Subsets in the Generation of a CD8+ T Cell Response Following Pulmonary Vaccinia Viral Infection
… to a pathogen, T cells circulating through lymph nodes (LN) must be alerted to the presence of infection in the periphery. This occurs as a result of presentation of pathogen derived epitopes on professional antigen presenting cells (APC), primarily dendritic cells (DC). While an important …
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