Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 186 for “"lung disease"”.
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Lung disease diagnosis from gene expression profiles
Lung diseases include some of the most widespread and deadly conditions known to affect people in the US today. One of the main challenges in treating lung disease is the difficulty of diagnosis. Clinical diagnosis remains largely dependent upon symptomatic-based diagnoses; many cases can be either …
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The Role of Silicates in Interstitial Lung Disease
Interstitial Lung disease (ILD), produces disruption of alveolar walls with loss of functionality and accumulation of scar tissue. Asbestosis and silicosis are the ILD produced by the inhalation of asbestos fibers or silica particles respectively. An increase in prostacyclin release after exposing …
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The Role of Silicates in Interstitial Lung Disease
Interstitial Lung disease (ILD), produces disruption of alveolar walls with loss of functionality and accumulation of scar tissue. Asbestosis and silicosis are the ILD produced by the inhalation of asbestos fibers or silica particles respectively. An increase in prostacyclin release after exposing …
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Obstructive Lung Disease among tobacco farmers in Malawi
… linked to the development of chronic respiratory diseases. This study was aimed at determining the prevalence of obstructive lung disease among tobacco farmers in Malawi and its association to nicotine and pesticide exposure. Methods A cross-sectional study was conducted comprising of 279 current …
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Prognostication and disease monitoring in fibrotic interstitial lung disease
Introduction Fibrotic interstitial lung disease (f-ILD) causes significant morbidity and mortality worldwide. Progressive pulmonary fibrosis (PPF) describes a cohort of patients who develop progressive disease despite standard treatment. To provide optimal care, it is vital to identify those …
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Beta-adrenoceptor blockade and stimulation in obstructive lung disease
Contains fulltext : mmubn000001_029174244.pdf (Publisher’s version ) (Open Access)
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Occupational exposures and the development of lung disease in Minnesota miners
… in northeastern Minnesota and the development of lung disease. This research was conducted as part of the Minnesota Taconite Workers Health Study, an epidemiologic study looking at the potential health effects from work in the taconite industry. There are three areas of research within this …
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Investigating genetic and molecular factors contributing to sexual dimorphism in lung disease
Differences in disease susceptibility, progression and severity patterns exist between males and females. Asthma and chronic obstructive pulmonary disease (COPD) are pervasive respiratory diseases that demonstrate sexual dimorphism. Male children experience increased asthma rates and worse health …
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The Role of A2B Adenosine Receptor Signaling In Adenosine Dependent Lung Disease
Chronic lung diseases and acute lung injuries are two distinctive pulmonary disorders that result in significant morbidity and mortality. Adenosine is a signaling nucleoside generated in response to injury and can serve both protective and destructive functions in tissues and cells through …
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The Hypoxic Adenosine Response Modulates Macrophage Differentiation and Contributes to Lung Disease
… pulmonary fibrosis (IPF) is a chronic lung disease which affects 5 - 8 million individuals worldwide and 200,000 individuals in the United States alone. Although prevalent, we do not know what causes IPF and no effective curative treatment exists for this disease. Our laboratory has …
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Strategies to Target the Bone Morphogenetic Protein Signalling Pathway in Lung Disease
Lung disease and lung injury are responsible for 20% of deaths of the Irish population every year, and the country has the 2nd highest death rate in Europe for respiratory diseases. Conditions related to the respiratory system are the second largest long term illness by young adults. Lung cancer is …
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Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children
… to correlate this with the severity of HIV-disease, and to assess the impact of anti-retroviral therapy (ART). Method: A prospective longitudinal study evaluating clinical, immunological and radiographic parameters at regular intervals over a minimum of 24 months. CXR abnormalities were …
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Effects of xanthine oxidase inhibitors in pulmonary hypertension associated with chronic lung disease
Chronic lung diseases are often complicated with pulmonary hypertension (PH). This can lead to disability and poor prognosis. Oxidative stress has been implicated in the development of PH and right ventricular hypertrophy (RVH).A possible new way to treat lung disease related pulmonary hypertension …
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A retrospective review of lung disease in adolescents living with human immunodeficiency syndrome
Chronic lung disease (CLD) is common in adolescents living with Human Immunodeficiency Virus (ALHIV), many of whom have survived early childhood respiratory infections and immune dysregulation. Little is known about the characteristics of ALHIV with CLD. Understanding the characteristics of this …
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The characteristics of intersitial lung disease patients attending Groote Schuur Hospital Respiratory clinic
Rationale: Interstitial lung diseases (ILDs) encompass a myriad of clinical conditions posing diagnostic challenges in low-income settings. The incidence of Idiopathic pulmonary fibrosis (IPF) is unknown on the African continent. Groote Schuur Hospital (GSH) provides a tertiary referral and …
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Image analysis methods for diagnosis of diffuse lung disease in multi-detector computed tomography
… monitoring of the onset and progression of the disease. Multidetector CT (MDCT) allows acquisition of volumetric datasets with almost isotropic voxels, enabling visualization, characterization and quantification of the entire extent of lung anatomy, thus lending itself to characterization of …
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