Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"low-molecular-mass"”.
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Expression and function of low molecular mass PLA2S
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Low molecular mass proteins as markers for renal function and dialysis efficiency
… were tested for their capacity to remove low molecular mass proteins (LMMP) and thus their potential for treatment of patients with kidney failure. The LMMP have been proposed to be uraemic toxins and must therefore be removed from the circulation. The result from our study showed that …
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Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent
It has been found that low molecular mass copper(II) complexes are effective in the treatment of rheumatoid) arthritis (RA). Increasing the amount of copper associated with low molecular mass ligands in plasma helps to alleviate the symptoms of rheumatoid arthritis. Low molecular weight ligand, …
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The development of new methods for the assessment of oxygen radical-mediated oxidative damage to biomolecules with special reference to lipids
… hydroxyl radical (.OH) which is mediated by low-molecular-mass iron chelates such as iron-citrate complexes. The .OH radical is extremely reactive and proving its formation in vivo is very difficult. Hence, assays for the assessment of .OH radical activity in the inflamed rheumatoid joint …
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An investigation into the bioconversion of South African sub-bituminous coal by Trametes species and Trichoderma atroviride
… African (SA) sub-bituminous coal to produce low molecular mass intermediates which may be used in further processes to yield value-added compounds. Low rank coals (LRC), which are less desirable for combustion processes than high rank coals, are more amenable to biodegradation due to their …
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Molecular characterisation of the mechanisms of compatible solute accumulation in Listeria monocytogenes
… to the accumulation of a restricted range of low molecular mass solutes compatible with cellular function. Accumulated to high internal concentrations in hyper-saline environments, compatible solutes, either transported into the cell or synthesized de novo, play a dual role: helping to …
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A chromatographic investigation into the reactions of urea and formaldehyde.
… rapid reproducible method for investigating the molecular mass distribution of urea formaldehyde resins by size exclusion chromatography has been developed. By using lithium chloride in dimethylformamide as the solvent for chromatography, solubility and molecular association problems have been …
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Synthesis of Mycobacterial Ergothioneine biosynthetic pathway metabolites
… (MSH) and ergothioneine (ESH) as their principal low molecular mass thiol instead. Ergothioneine has been known for a while as an anti-oxidant; however its role as a protective thiol in Mycobacterium tuberculosis is still undefined. Present knowledge indicates that ergothioneine may play a …
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Synthesis of thiohistidines and its metabolic pathway precursors
… mycothiol and ergothioneine as their principal low molecular mass thiols. It is only very recently that the link between ergothioneine and tuberculosis disease has started to emerge, these studies suggested that ergothioneine is essential for the survival of Mycobacterium tuberculosis, the …
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Bioabbaubare Polymernetzwerke mit Formgedächtniseffekt als Matrix für Wirkstofffreisetzungssysteme
… properties for controlled delivery of low molecular mass drugs. A polymer network based on oligo[(e-hydroxycaproate)-co-glycolate]dimethacrylates and butylacrylate with a semi-crystalline switching segment is used for the systematic investigation of the influence of the polymer matrix …
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Regulation and function of hyaluronan binding by CD44 in the immune system
… and the size of hyaluronan itself, with high molecular mass hyaluronan having a greater effect than intermediate or low molecular mass hyaluronan. The addition of hyaluronan to pre-activated Jurkat T cells induced rapid cell death independently of Fas and caspase activation, identifying a …
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Restriction of Retrotransposition and Retroviral Infection by RNase L and APOBEC3G
… of A3G from enzymatically-inactive high molecular mass complex to enzymatically-active low molecular mass complex. Virion-associated A3G exhibited elevated cytidine deaminase activity in the presence of RNase L. These results supported a regulatory mechanism for A3G during HIV-1 …
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Bioanalytical Methods Development for Detection and Characterization of Labile Metal Pools in Escherichia Coli
Low-molecular-mass (LMM) transition metal complexes are thought to play essential roles in metal ion trafficking, regulation, and signaling in biological systems. Their chemical identities remain largely unknown due to their rapid ligand-exchange rates and weak metal-ligand bonds. Lack of chemical …
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Development of dermally absorbed copper(ii) complexes as potential anti-inflammatory drugs
… CW-EPR spectroscopy, 1H NMR, ESI-MS and molecular modelling calculations. The presence of sarcosine did not significantly affect the stability of the complexes. Several species were found to exist in solution depending on the pH, but at pH 7, the CuLH-2 species predominated for all four …
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THE RELEASE OF CONTAMINANTS BY LEACHING FROM BOIL-IN BAG LAMINATES
… the high migration result. Calcium stearate and low molecular mass oligomers (non-toxic) are suggested as the cause of the flocculate. More importantly, the contribution of potentially toxic aromatic amines to the global migration result was determined. Apparent aromatic amine levels in aqueous …
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Investigation into the membrane interactive properties of the escherichia coli low molecular weight penicillin-binding proteins
… a protein complex(es) which could include low molecular mass penicillin-binding prpteins (PBPs). These proteins include PBP4, PBP5 and PBP6 which are penicillin sensitive enzymes associated with the periplasmic face of the inter membrane. The levels of these associations have been linked to …
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Isolation and structure elucidation of bioactive secondary metabolites from marine sponges and sponge-derived fungi
Low-molecular mass natural products from bacteria, fungi, plants and marine organisms exhibit unique structural diversity which are of interest for the identification of new lead structures for medicinals and agrochemicals. In the search for bioactive compounds from marine sponges and …
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Investigation into the membrane interaction of E.coli Pencillin binding protein 4
The low molecular mass penicillin-binding proteins (PBPs) of E. coli play a regulatory role in the terminal stages of peptidoglycan biosynthesis. PBPs 4, 5 and 6 have been shown to possess DD-carboxypeptidase activity with PBP4 also having an endopeptidase activity. PBP5 and 6 are proposed to …
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Long-term Effects of Fertilization on Phosphorus Biogeochemical Pools in Forest Soils
… P compounds detected and were present in very low quantities. The significant increase of NaOH/EDTA extractable P in the soil surface of the VA site suggested there has been a beneficial long-term effect of fertilization similar to the observations from the Mehlich-3 soil test. Results from …
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Hyperbranched polyesters for polyurethane coatings: their preparation, structure and crosslinking with polyisocyanates
… (90°C) in order to avoid undercure. The lower reactivity of phenolic OH groups prevents the reaction from being too fast at that temperature. A drawback of the polyurethanes based on the aromatic polyesters-polyols prepared is the lower thermal stability of their urethane bonds, if …
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