Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"locally advanced"”.
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Quantitative Ultrasound Characterization and Monitoring of Locally Advanced Breast Cancer
… (RF) ultrasound data were acquired from locally advanced breast cancer (LABC) patients prior to treatment. Results suggested that a multiparameter QUS model can sensitively (88%) and specifically (91%) differentiate breast tumours from surrounding normal tissue. Furthermore, a local …
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Preoperative Chemoradiotherapy of Locally Advanced Rectal Cancer: Preliminary Results of BID Fractionation
… is an effective modality for patients with locally advanced rectal cancer. This study was designed to evaluate the efficacy, tolerance, and toxicity of preoperative chemoradiotherapy (CRT) using BID fractionation in patients with locally advanced rectal cancer. PATIENTS AND METHODS: Between …
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Improving Dose-Response Correlations For Locally Advanced Nsclc Patients Treated With Imrt Or Pspt
<p>The standard of care for locally advanced non-small cell lung cancer (NSCLC) is concurrent chemo-radiotherapy. Despite recent advancements in radiation delivery methods, the median survival time of NSCLC patients remains below 28 months. Higher tumor dose has been found to increase survival but …
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Localized and disease-selective drug delivery using adhesive hydrogels for treatment of locally advanced TNBC
… of invasive breast cancers, and about 15% are locally advanced at time of presentation. TNBC is negative for estrogen and progesterone receptor, as well as for HER2, and hence it is not treatable with common endocrine treatment such as tamoxifen or Herceptin. Systemic neoadjuvant therapy has …
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Living with locally advanced rectal cancer: an exploration of the everydayness of living with rectal cancer
… that increasingly individuals are living with advanced cancer, yet services remain disease orientated. This thesis has documented the process of undertaking a longitudinal qualitative study to explore the everydayness of living with locally advanced rectal cancer. The study has identified how …
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Chemoradiotherapy in locally advanced head and neck cancer patients: efficacy, toxicity and impact on quality of life
Contains fulltext : 199078.pdf (Publisher’s version ) (Open Access)
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Dysphagia progression-free survival in patients with locally advanced and metastatic oesophageal cancer receiving palliative radiation therapy
Purpose: In patients with advanced oesophageal carcinoma palliation of dysphagia is important to maintaining a reasonable quality of life. The primary aim of this study was to determine the dysphagia progression-free survival (DPFS) in patients with advanced oesophageal carcinoma treated with …
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Development of a prognostic and predictive tool for chemotherapy response in patients with locally advanced and metastatic pancreatic adenocarcinoma
… with the majority of patients diagnosed at an advanced or metastatic stage—well beyond the window for curative surgical intervention. For these individuals, systemic chemotherapy remains the cornerstone of treatment. However, the absence of validated prognostic biomarkers, a lack of consensus …
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Late radiation proctitis : the incidence and contributing factors in patients with locally advanced cervical carcinoma treated at Pretoria Academic Hospital
The purpose of the thesis is to determine the incidence of late radiation proctitis in patients treated with radical radiotherapy in Pretoria Academic Hospital during a peroid when hypofractionated radiotherapy and external boosts were being utilised for the treatment of advances carcinoma of the …
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Volumetric modulated Arc Therapy versus 3D conformal radiotherapy in the treatment of locally advanced cervical cancer. A single institution, comparative dosimetric study
… Radiotherapy is essential in the management of locally advanced cervical cancer (LACC). Generally, VMAT is thought to achieve higher conformity to the Planned Target Volume (PTV) and better sparing of organs at risk (OAR) when compared to 3D-CRT. This study focused on these principles as it …
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Comparison of two neoadjuvant chemotherapy in locally advanced breast cancer patients; Adriamycin and Docetaxel (AD) versus Adriamycin, Cyclophosphamide followed by Paclitaxel (AC-T)
… of the standard treatmentfor the patients with locally advanced breast cancer and is an option for the patients with operable breast cancer. Such as adjuvant chemotherapy in breast cancer, anthracycline and taxane-based regimens have been studied and investigated as neoadjuvant setting. But, no …
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The Role of Drug Resistance-Related Proteins as Prognostic Factor in Patients with Locally Advanced Non-Small Cell Lung Cancer Treated with Concurrent Chemoradiotherapy
"국문요약 차례 그림차례 표 차례 서론 연구 대상 및 방법 결과 고찰 결론 참고문헌 ABSTRACT"
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Patterns of care and outcomes for women with locally advanced cervical cancer, treated with curative intent, between 2013-2017 at a tertiary centre in South Africa
… Africa. The standard treatment guidelines of locally advanced cervical cancer (LACC) is external beam radiation followed by brachytherapy with concurrent platinum based chemotherapy. The aim of this study is to evaluate the patterns of care and outcomes for patients with LACC (Stage IB1 – IVA) …
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Influence of molecular and genetic factors of the organism΄s antioxidative system on cervical carcinogenesis and the role of these factors in treatment of locally advanced cervical cancer /
… in Europe. Approximately in 50% of the cases locally advanced cervical cancer is diagnosed, despite screening programme. In order to more effectively diagnose and treat this disease, it is necessary to deepen knowledge about cervical cancer development mechanisms, identify markers that could …
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Comparison of 18F-Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (18F-FDG PET/CT) and conventional imaging (CI) for locally advanced breast cancer staging: a prospective study from a tertiary hospital cancer centre in Western Cape
… metastases is one important prognostic factor in locally advanced breast cancer (LABC), accurate staging at diagnosis is crucial to ensure patients receive the appropriate treatment. Increasing evidence shows that the use of 18F-FDG PET/CT for disease staging of LABC may improve diagnostic …
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Advanced breast cancer: A retrospective review comparing two palliative radiotherapy protocols used at Groote Schuur Hospital between 2010 and 2013
… breast palliative regimes used in patients with locally advanced or metastatic breast cancer between 2010 and 2013 in a single institution. Methods: Compliance to treatment, acute skin reactions, progression free and overall survival were retrospectively evaluated in patients who received …
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FDG-PET in Cervical Cancer - Translational Studies
… the extent of the disease in primary staging of locally advanced cases and in re-staging of recurrent disease. The treatment plans were altered as a result of the FDG-PET findings for one fourth of the patients. Surveillance FDG-PET 6 months after surgery for early-stage disease showed no …
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Corrélation of Plasma Osteopontin Levels and 3D US Imaging with Tumor Response to Neoadjuvant Therapy
Locally advanced breast cancer (LABC) is an aggressive form of pre- metastatic breast cancer, with an expected five-year survival rate of 30-42%. The current standard of treatment is neoadjuvant therapy; however there is a limited ability to monitor tumor response to this treatment. This study …
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A retrospective audit of young patients diagnosed with cervical cancer over ten years at Groote Schuur Hospital, Cape Town between 1 January 2003 and 31 December 2012, and their outcome at five-year follow-up compared to women in the prior decade
… In the developing world, late presentation, advanced-stage disease and a poorly run screening programme (covering only 55% of the South African population) are all contributing factors to this statistic. Approximately 20% of all South African women in their reproductive age are also HIV …
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Ankstyvosios diagnostikos programos poveikio sergamumui priešinės liaukos vėžiu Lietuvoje vertinimas /
… resulted in decreased incidence of localized and locally advanced prostate cancer across 50-75 years men group. Results of the study suggest that men younger than 60 years need to be involved in early detection program by additional means of information. The active surveillance should be widely …
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