Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"local therapy"”.
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Antimikrobielle Therapie der Hornhaut : die Pharmakokinetik in der lokalen Therapie und ihre Optimierung durch den Mikrotrepan; am Beispiel von Ciprofloxacin und PVP-Jod
… of two different substances in the topical therapy of the cornea. The main focus of each part of the study was different, as described below. Methods: In the first part, we used NMR spectroscopy (nuclear magnetic resonance) to analyse drugs containing fluor and to detect them in the anterior …
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Localized and disease-selective drug delivery using adhesive hydrogels for treatment of locally advanced TNBC
… of invasive breast cancers, and about 15% are locally advanced at time of presentation. TNBC is negative for estrogen and progesterone receptor, as well as for HER2, and hence it is not treatable with common endocrine treatment such as tamoxifen or Herceptin. Systemic neoadjuvant therapy has …
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Interstitial laser thermotherapy (ILT) of breast cancer - Methodology and immunological responce
Interstitial laser thermotherapy (ILT) is an attractive form of local therapy against cancer because of its anti-tumor immune activity. The aim of this work was to evaluate ILT in breast cancer with respect to technique, changes in tissue immunocompetent cells and effect on prognosis. The method is …
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Contributions of type 2 IP3 receptors to intercellular adhesions and invasion of glioblastoma cells
… impossible and allowing recurrence after local therapy. Ca2+ is an ubiquitous intracellular messenger. Ca2+ signals are often initiated by inositol 1,4,5-trisphosphate receptors (IP3Rs), which mediate Ca2+ release from the endoplasmic reticulum. Mammals express three IP3R subtypes …
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Lokale Therapie der Sauerstoff-induzierten angioproliferativen Retinopathie im Mausmodell : Small Molecule Receptor Tyrosine Kinase Inhibitors
Das Glykoprotein Vascular endothelial Growth Factor (VEGF) ist einer der Hauptmediatoren der Angiogenese und zählt zu den wichtigsten Faktoren in der Pathogenese der angioproliferativen Retinopathie. Die Wirkung von VEGF wird über spezifische Rezeptoren vermittelt, die zur Familie der …