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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"local anaesthetic"”.
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Synthesis of pyrazoline derivatives and an examination of their local anaesthetic activity
(1) From p-alkoxy and m-p-dialkoxy benzylidene acetones, utilising the Mannich reaction, a series of unsaturated alkyl amino ketones of the type (I)
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The interaction of three local anaesthetic agents with hepatic microsomal cytochrome P-450
… P-450 on the binding and metabolism of three local anaesthetic agents: lidocaine, mepivacaine and bupivacaine has been investigated. All three local anaesthetic agents bound to the type I binding site of cytochrome P-450, which is characteristic of substrate binding to cytochrome P-450, and …
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Does the use of video improve patient satisfaction in the consent process for local-anaesthetic urological procedures?
… urological outpatient procedures performed under local anaesthesia. Methods Patients undergoing the following procedures were approached for recruitment: flexible cystoscopy with or without biopsy, transrectal ultrasound-guided prostate biopsy or flexible cystoscopy with insertion or removal of a …
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Descending Activation of Cockroach Giant Axons and Alterations of Their Conduction Velocity by the Local Anaesthetic-Like Activity of Nicotine
Made available in DSpace on 2015-05-14T14:58:35Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7317540.PDF: 6948398 bytes, checksum: 952b733917dcf56626507b34f6162b2d (MD5) Previous issue date: 1973
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Survival after local anaesthetic overdose : a comparison of the success of resuscitation after established cardiotoxicity caused by ropivacaine or bupivacaine
… is to review the pharmacology and toxicity of local anaesthetics, particularly highlighting the differences between bupivacaine and ropivacaine and to present an experiment attempting to establish whether ropivacaine is a safer drug, once cardiotoxicity has occurred.
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Epidural analgesia
… rather high, and toxic reactions to the injected local anaesthetic drug were not infrequent. The lumbar route was then tried and, rather surprisingly, this proved somewhat easier. Failures were fewer, and because a slow unforceful injection could be made (in contradistinction to caudal block), …
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Cardiovascular, autonomic and neuropathic physiology and their involvement in the extra-articular manifestations of hypermobility disorders
… syndrome (POTS) (8, 9), chronic pain (8) and local anaesthetic inefficacy (8, 10, 11) are recognised as being highly burdensome (3, 6, 9) research regarding their causes is scarce, limiting our understanding of their association with hypermobility and the development of evidence-based care. …
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Exploring patients' experience of dental implant surgery with or without intravenous conscious sedation: a qualitative study
… IVCS, while 10 had dental implants placed with local anaesthetic (LA) only. Thematic analysis revealed that emergent themes fitted appropriately with 3 different time points along the dental implant surgical journey (Pre-operative, Intra-operative and Post-operative experiences). Data and …
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A pharmacometric approach to optimal use of second line drugs for multidrug-resistant tuberculosis
… design, investigate whether the addition of a local anaesthetic reduces kanamycin-related injection pain, and explore effects on kanamycin pharmacokinetics. 4. Using geometric mean ratios, compare the exposures of crushed versus whole formulations of pyrazinamide, moxifloxacin, ethionamide, …
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Improving pain management for children
… used in paediatric clinical practice, namely local anaesthetics, opioids, non-steroidal anti-inflammatory drugs (NSAIDs) and paracetamol. In addition, control of the stress responses to tracheal intubation and to surgery has been studied with the availability of newer potent short-acting …
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Prospective study to compare the difference in cerebral perfusion in patients undergoing shoulder surgery with the standard beach chair position compared to 30˚ inclination
… than 18 years, ASA grade 4 and 5, allergy to local anaesthetic, pre-existing coagulopathies or a failed interscalene block were excluded. Cerebral oxygenation were measured with the INVOS system along with the other standard observations in theatre. The 2 most important parameters measured …
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Perioperative caearean section pain management at Groote Schuur hospital ? an audit
… were done poorly (intravenous paracetamol 15.5%, local anaesthetic 15.5%) and two postoperative interventions were done well (oral paracetamol 89.3%, intramuscular morphine 100%). Conclusion: Current clinical practice for the perioperative pain management of caesarean sections at this hospital …
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Consolidating Approaches to Maximise Outcomes and Minimise Complications of Contemporary Cataract Surgery
… an intraocular lens, typically performed under local anaesthetic, transforms both vision and quality of life. This thesis explores several key aspects of contemporary cataract surgery, which is the most commonly performed surgical procedure in the world. The New Zealand Cataract Risk …
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Local anesthetic wound infusion versus standard analgesia in paediatric post-operative pain control : a randomised control trial
… and/or paracetamol (Perfalgan ®) infusion. Local wound infusion has been effectively utilized in adults with promising results but has not been prospectively tested in children undergoing different abdominal operations. The aim of this study was to compare continuous local anesthetic wound …
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Heart Rate Variability analysis in patients undergoing local anesthesia
… the effect of HRV during Brachial plexus block (local anaesthesia), applied using the axillary approach. The hypothesis was that, such investigation will enable the detection of possible changes in the dynamics of the cardiovascular system due to the intravenous introduction of anaesthetic drugs …
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Reflex inhibition of the human quadriceps in the presence of knee joint damage
… by per-operative infiltration of the knee with a local anaesthetic (Chapter 3). Prolonged voluntary tourniquet ischaemia in normal subjects did not alter subsequent quadriceps function, indicating that the reduced NVA observed in the meniscectomy patients was not due to ischaemia (Chapter 4). …
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Multidisciplinary management of Complex Regional Pain Syndrom Type 1 in children admitted to Red Cross War Memorial Hospital: A case series describing long-term effects on pain, function and quality of life
… and amytriptilline. One child received epidural local anaesthetic infusion. On average, pain scores improved by 67.8% by the time of discharge. At an average long-term follow-up interval of 10.3 months (ranging between 6 to 21 months), the pain score had worsened by 10.5% compared to discharge. …
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Study of damage to peripheral nerves caused by anaesthetic needles during regional anaesthesia
… and provides real time visualization of local anaesthetic spread. However, the risk of nerve trauma still remains. A recent meta-analysis of randomized controlled trials has described the incidence of transient neuropathy secondary to Ultrasound Guided Regional Anaesthesia (UGRA) in 7% of …
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Development of stationary phase materials and methods for analysis of pharmaceuticals via high-performance liquid chromatography and electrochemical detection
… rapid separation and sensitive detection of the local anaesthetic TCH and the nasal decongestant OZH combining the high separation efficiencies and the short analysis time of core-shell silica particles with the sensitivity of a BDD electrode. The chromatographic separation was carried out using …
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Comparison of fine needle aspiration cytology and cell block to formal histology of small subcutaneous mass lesions in children. a prospective study at Red Cross War Memorial Children`s Hospital
… preoperative admission, starvation, a general anaesthetic, an operative procedure, postoperative pain, higher costs, as well as time taken for results, while FNAC can be performed as an outpatient procedure with local anaesthetic if needed. Objective This study aims to primarily determine the …