Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"liquid culture"”.
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Evaluation of Different Methods for the Detection of Mycobacterium bovis in Lymph Node Tissue
… 960 a high capacity, automated, non-invasive liquid culture system was proposed as an alternative to the BACTEC 460, a semi-automated, radiometric liquid culture system, for the growth of mycobacteria from bovine lymph node (LN) tissues. A limit of detection study for Mycobacterium bovis, …
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Population pharmacokinetics and pharmacokinetic-pharmacodyamic modeling of antitubercular drugs
… data was comprised of weekly sputum liquid culture (using mycobacterial growth indicator tubes) time to detection results from 144 patients during the first 2 months of treatment. The effect of drug exposure on patient outcomes was investigated. To determine the adequacy of ofloxacin …
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A multilocus phylogeny of Hericium fungi in Canada and their production of Erinacine A
… nerve-growth factor stimulatory activity, and liquid culture conditions were modified for enhanced erinacine A biosynthesis in each species. Together with clear distinction of the species in Hericium, the findings presented herein will contribute to natural products research and medical …
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Identification of HIV protease mutants with improved specificities toward an Alzheimer's Disease associated peptide sequence
… profiles are readily assessed via E. coli liquid culture Pgal activity assays.
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The ultrastructure of a marine luminous bacterium
… solid medium, cells from actively luminescent liquid culture were found to possess certain peculiar features. The most notable of these were tetrads, cells in which ingrowth of the cytoplasmic membrane causes the contents to be divided up into four protoplasts within the cell wall. Small …
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Genetic Studies of the Effect of Serotype Switching in O1 Vibrio cholerae
… grown in isolation, but when grown together in liquid culture the serotypes reached an equilibrium of 80% Ogawa to 20% Inaba. One experiment to illustrate serotype switching by applying a selection pressure using antibodies was performed. The experiment generated 8 novel Inaba mutations, one of …
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Bacteriophages and their hosts: an investigation into veterinary Pseudomonas aeruginosa strains and the phages isolated against them
… tested for their ability to clear infection in liquid culture, using the lab strain PA01. Those showing increased ability to clear infection were then selected for experiments looking at their ability to disrupt growth of clinical strains, both in liquid culture and in biofilms. Although phages …
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Visualisation of bioluminescent Vibrio midae SY9 K811 in juvenile Haliotis midae abalone using non-invasive bioluminescence imagining
… monitored in murine models or mammalian tissue culture systems. In order to determine whether BLI could be used to monitor bacterial-host interactions in an invertebrate system, the probiotic bacterium Vibrio midae SY9 was genetically labelled with a bioluminescent plasmid (pKluxCat) containing …
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Towards synthetic ecology : genetically programmable 4-module population control system in yeast
… ecology, researchers have been trying to culture pure and mixed species in different conditions to elucidate the rules behind the interactions. However, the studies have been complicated by multiple variables at both the genotype and phenotype levels. To address these challenges, I …
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Influence of Varying Inorganic Nutrients Supply on Ergosterol and Glucosamine Concentrations and Biomass Nutrient Stoichiometry in Ectomycorrhizal Fungi
… Six ECM fungal species were grown in liquid culture under varying nitrogen and phosphorus concentrations and ratios to assess how exogenous nutrient supplies affect fungal biomass stoichiometry and the degree of elemental homeostasis. Additional studies also examined nutrient and ratio …
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Signalling Molecule Production by Escherichia coli and Campylobacter jejuni
… tested induced activity in the Agrobacterium liquid culture bioassay, in a growth-dependant manner, indicating the possible presence of an exogenous AHL. Comparative analysis of the genome sequenced C. jejuni strain, NCTC 11 168-GS and its clinical counterpart, C. jejuni NCTC 11168-0, has …
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Growth of Chlorella vulgaris and Chlamydomonas reinhardtii for biodiesel production and carbon dioxide capture
… algae was 20% of the maximum obtained in liquid culture, indicating the need to future optimize this novel method for CO2 capture.
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Investigations of the postantibiotic effect and related antibacterial activity of meropenem.
… or belonged to the National Collection of Type Cultures. In an attempt to determine possible mechanisms of resistance of the test organisms to antibiotics, they were analysed for their plasmid content and for their Beta-lactamase profiles. Post antibiotic effect is the delayed regrowth of …
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Novel and newer nucleic acid amplification tests for the diagnosis of TB
… were collected from patients with suspected TB. Liquid culture served as the reference standard for the diagnosis of definite TB. Accuracy was evaluated according to HIV and smear microscopy status, where appropriate. The relationship between test performance and bacterial load (culture …
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Utilization of the Phanerochaete chrysosporium ligninolytic system and the potential for toxaphene degradation
… halide pesticide toxaphene were explored in pure liquid cultures. The effects of culture growth temperature and toxaphene concentration were evaluated. The extent of toxaphene conversion with time was determined using three different indicators; toxaphene gas chromatographic elution patterns, the …
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“Mycoremediation” of PFAS: application of wood decay fungi and natural wood substrates to investigate the tolerance, degradation, and sequestration capacity of fungi for perfluorocarboxylic acids:
… and defluorination was measured under solid and liquid culture methods using the selected methodology. The capacity to degrade and remove PFAS was confirmed leading to the development and investigation of a fungal-based sorbent system and investigation of PFAS sequestration by wood-based …
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The role of phospholipids in the growth and development of Streptomyces
… in S. coelicolor, mRNA from plate grown-cultures was extracted at different developmental stages and analyzed by RT-PCR to detect expression of the phospholipid biosynthetic genes. No amplification products were detected in the absence of mRNA confirming that amplification products are …
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Bioreactor design for scaleup of Catharanthus roseus hairy root cultures for production of indole alkaloids
… vincristine and vinblastine. Hairy root cultures are an attractive alternative for the production of plant derived secondary metabolites. C. roseus hairy root cultures were established in our laboratory by A. rhizogenes mediated transformation of C. roseus seedlings prior to the beginning …
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Analysis of the Tumour Microenvironment in CLL
… in the body but die rapidly by apoptosis when cultured in the lab, suggesting that CLL cell survival can be modulated by tumour cell interactions with the microenvironment in vivo.<br/>The first part of the thesis describes in vitro assays which demonstrated that CLL cell contact with …
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