Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 324 for “"liposomes"”.
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Turning stealth liposomes into cationic liposomes for anticancer drug delivery
… reported passive tumor targeting by PEGylated liposomes (stealth liposomes) have resulted in their higher tumor accumulation. However their interaction with cancer cells has been minimal due to the steric hindrance of the PEG coating. This dissertation reports two approaches to enhance the …
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Receptor mediated targeting of liposomes
The targeting of liposomes to cells and the delivery of the liposomal contents into the cells have been investigated using either α-melanocyte stimulating hormone or Ricin-B-chain as ligands for promoting the binding of liposomes to cells. α-melanocyte stimulating hormone has been conjugated to …
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Innovatives liposomes for overcoming biological barriers
… this thesis work were prepared and characterized liposomes and liposomes modified with a coating of chitosan called chitosomes. Through these structures were conveyed drugs of natural origin with anti-inflammatory and antioxidant properties: quercetin,phycocyanin and curcumin. The liposomes …
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GDGT liposomes for oral peptide delivery
Τα αρχαία αποτελούν διακριτή επικράτεια της ζωής και χαρακτηρίζονται από τη μοναδική δομή των μεμβρανικών τους λιπιδίων, τα οποία φέρουν ισοπρενοειδείς αλυσίδες συνδεδεμένες με αιθερικούς δεσμούς. Χάρη στα ιδιαίτερα αυτά χαρακτηριστικά, τα λιπίδιά τους μπορούν να σχηματίζουν εξαιρετικά σταθερά …
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Resistive Pulse study of Vesicles and Liposomes
In this work, the properties of the liposomes, the artificially created vesicles by various methods, are explored by a resistive pulse method using micropipettes. The fact that vesicles are fundamental in the wide range of functionalities they fulfill as organelles strengthen the desire of …
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Polymerized liposomes as potential oral vaccine delivery vehicles
Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1997.
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Echogenic Liposomes For Nitric Oxide Delivery and Breast Cancer Treatment
<p>Liposomes, also known as nontoxic, biodegradable, and non-immunogenic therapeutic delivery vehicles, have been proposed as a carrier for drugs and antitumor agents in cancer chemotherapy. Echogenic liposomes (ELIP) have the potential to entrap air or bioactive gas to enhance acoustic …
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Development of environmentally benign microencapsulation with polymer microspheres and liposomes
Microencapsulation means applying a shell-like coating to encapsulate the contents of interest in a particle form with a size range of few micrometers or below. In this work, aqueous liposome systems and polymer based encapsulation of fine particles in supercritical CO_2 were studied. Compared to …
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Pressure Effects on Liposomes, Biological Membranes and Membrane-Bound Proteins
The phosphatidylcholine vesicles were examined by steady state polarization fluorometry under pressure in the range of 1 bar to 2 Kbar. Isothermal pressure-induced phase transitions were observed in dipalmitoylphosphaditylcholine and dimyristoylphosphatidylcholine vesicles incorporated with …
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Drug-encapsulating EGF-sensitive liposomes for EGF-overexpressing cancer therapies
… epidermal growth factor (EGF)-sensitive liposomes for EGF-overexpressing cancer therapies have been developed and studied. These drug-encapsulating liposomes remain inert until they are exposed to an abnormal concentration of EGF. As a drug delivery system, these drug-encapsulating …
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Trans-2-aminocyclohexanol as a pH-sensitive conformation switch in liposomes
… Fluorescence leakage assay was conducted on liposomes that encapsulated with ANTs/DPX fluorescence dyes. For certain special designed cyclohexane compounds, the pH triggered lipid conformation change will rupture liposome membrane, release the encapsulated content, and thus help them escape …
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Characterization of Triggerable Quinones for the Development of Enzyme-Responsive Liposomes
… From all of the carriers, stimuli-responsive liposomes have been studied extensively, but only a handful have been enzyme-responsive liposomes. Therefore, the field of endogenous proteins as activators of liposomes is a fertile field worthy of exploration. The research described in this …
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Bioadhesive Microparticles and Liposomes of Anti-Parkinson Drugs for Nasal Delivery
… to develop novel bioadhesive microspheres and liposomes entrapping the anti-Parkinson drugs ropinirole hydrochloride (RH). The microspheres were prepared via spray drying in combination with chitosan or sodium alginate and the liposomes were prepared using the ethanol-based proliposome method. …
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