Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"lipophosphoglycan"”.
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Chemical synthesis of <em>Leishmania </em>lipophosphoglycan structures conjugated to a biotin moiety
Leishmaniasis is the second largest parasitic killer in the world (after malaria) responsible for an estimated 500,000 cases each year worldwide. Visceral leishmaniasis infections (i.e. internal organs) are more complicated to diagnose due to the lack of visible symptoms. Current tests of the …
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Solution and solid-phase synthesis of potential carbohydrate vaccines for leishmaniasis and malaria
… found on the parasite cell surface lipophosphoglycan is described. The synthetic material was used to create two novel immungens that are currently being evaluated in an animal model. New methods were also developed for an automated solid-phase synthesis that took a fraction of the …
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Estudo do papel do lpg2 na migração de células dendríticas infectadas por Leishmania infantum
… studies highlight the importance of Leishmania lipophosphoglycan (LPG) in the interaction with host cells, the parasite's survival mechanisms, and the establishment of infection. However, the relationship between LPG and dendritic cell migration remains to be elucidated, considering that these …
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Defining D-Arabinose Metabolism in <i>Leishmania major</i> and <i>Crithidia fasciculata</i>
… trypanosomatid parasites: Leishmania major lipophosphoglycan (LPG) Crithidia fasciculata lipoarabinogalactan (LAG) and Endotrypanum schaudinni glycoinositol phospholipids (GIPLs). The activated donor molecule of D-Arap has been identified in L. major as GDP-α-D-Arap. However, the source of …