Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"lipid loading"”.
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Protein-sphingolipid interactions and their role in immunity and disease
Sphingolipids are a diverse class of lipids involved in fundamental cellular processes. In addition to their role in membrane architecture, sphingolipids can act as bioactive molecules, regulate membrane protein function and be presented to the immune system as lipid antigens by CD1 family …
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Investigating iPSC-Derived Macrophage Stimulation with Oxidised Low-Density Lipoprotein as an Effective In Vitro Model of Foam Cells in Atherosclerosis
… causing intracellular accumulation of lipids. Existing studies have described potential foam cell-like populations using single cell RNA sequencing (scRNA-seq) of plaques, however due to known limitations of whole cell and more recent findings expanding our current knowledge of foam …
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Modification of Low Density Lipoprotein and the Effects of Modified Low Density Lipoproteins on the Endocytic and Secretory Repertoire of the Macrophage
… macrophages. Mouse peritoneal macrophages were lipid-loaded by three regimens modeling loading through the scavenger receptor (Ac-LDL cells), by extracellular matrix-bound LDL (DS-LDL cells), and conditions of reduced cholesterol acceptors in the medium (LS/01 cells). Increased cholesterol …