Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"link protein"”.
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Molekulare Zusammensetzung der extrazellulären Matrix im Patellar- und Quadrizepssehnenansatz frühkindlicher Patellae
… Tenascin sind stets in den Ansätzen zu finden. Link Protein lässt sich häufig in den Anheftungszonen nachweisen, während Aggrecan in rund zwei drittel der Fälle in der kindlichen Enthesis auftritt. Histomorphologisch stellt sich die Enthesis an beiden Enden der Patella als Faserknorpel mit …
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A Novel Role for HAPLN1 in Skeletal Development
… gene. HAPLN1 encodes Hyaluronan and Proteoglycan Link Protein 1, also known as Cartilage Link Protein, that is reported to stabilize the extracellular matrix (ECM) by binding hyaluronic acid (HA) and proteoglycans in multiple tissues. One variant, p.C304S, was predicted to disrupt a critical …
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CONNECTIVE TISSUE GROWTH FACTOR IS REQUIRED FOR CHONDROGENESIS
… l-sox5, type II collagen, aggrecan, decorin and link protein). Real-Time PCR, Western blot and Immunofluorescence reveal that CCN2 is required for the early stages of chondrogenesis, including expression of sox6 and aggrecan, but not type II collagen. Furthermore, focal adhesion kinase (FAK) was …
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Molekulare Zusammensetzung der extrazellulären Matrix des Ligamentum transversum acetabuli beim Menschen und bei Primaten
… sich unter anderem Kollagen II, Aggrecan und Link Protein. Diese mehr oder weniger deutlich ausgeprägten faserknorpeligen Areale lassen sich kausal auf in diesem Bereich auftretende lokale Druckbeanspruchungen zurückführen. Innerhalb des Bandes fällt die faserknorpelige Anpassung in …
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Characterization of the Role of SOX9 in Cartilage-Specific Gene Regulation
… genes, specifically Col9a1 and Cartilage Link Protein (CRTL1). Previously, enhancers of these genes containing single SOX9 binding sites were shown to be activated through SOX9 binding. However, the hypothesis was made that in cartilage-specific genes dimeric SOX9, as opposed to monomeric …
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Ultrastructure and nanomechanical properties of aggrecan from native cartilage and engineered tissue
… bottle-brush-shaped aggrecan consists of a core protein to which ~100 sulfated glycosaminoglycan (sGAG) chains are attached. Loss of sGAG is one early events in the pathogenesis of osteoarthritis and the resulting degradation of cartilage is irreversible due to its limited capacity for …
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hyaluronic acid networks in wound healing
… namely hyaluronic acid (HA) and associated proteins. In digits, these ECM networks were upregulated in regeneration, and their knockdown markedly impaired healing and enhanced deposition of collagen. Atomic force microscopy revealed that HA networks are important determinants of the …