Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"linear-quadratic model"”.
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Continuous low dose rate irradiation of the rat brain
… protocols can be derived using the linear quadratic theory, provided that quantitative radiobiological data for normal tissue (brain) is known. Thus, the aim of the current study is to test the radiation tolerance of the rat brain to low dose rate and fractionated radiation in order …
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Temporally Feathered Radiation Therapy under Uncertainty
… planning through novel stochastic optimization models that account for biological heterogeneity and uncertainty in organ-at-risk (OAR) responses. Building on the temporally feathered radiation therapy (TFRT) strategy, we develop a personalized, biologically informed treatment framework that …
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Development of hierarchical optimal control algorithms for interconnected nonlinear dynamical systems
… for optimal control of interconnected nonlinear systems. To achieve this, four basic hierarchical structures are developed by taking into account the manner in which real process measurements taken from interaction inputs are incorporated and utilized in the model-based optimal control …
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Ενισχυμένη ακτινοευαισθητοποίηση στη συνδυαστική βραχυθεραπεία με νανοσωματίδια χρυσού: Μια in vitro μελέτη για την ποσοτικοποίηση των κυτταρικών μηχανισμών και της απόπτωσης
… καμπύλες του Γραμμικού-Τετραγωνικού Μοντέλου (Linear Quadratic Model) και καμπύλες απόπτωσης, τόσο για τις κυτταρικές σειρές με νανοσωματίδια όσο και για εκείνες χωρίς, με στόχο τον προσδιορισμό και τον σχολιασμό της ραδιοευαισθητοποιητικής τους δράσης.
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Solid and hollow gold nanoparticles as radiosensitisers in combination with x-ray radiation and targeted radiopharmaceuticals
… alone and in combination on the growth of 3D MTS models. Radiosensitisation was measured by a decrease in clonogenic cell survival and quantified using the linear quadratic model. Association of radiosensitisation with changes in the cell cycle, dynamics of DNA double strand break (DSB) formation …
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Estimation of Variation For High-throughput Molecular Biological Experiments With Small Sample Size
… effects due to plates and batches. We propose a linear mixed-effect modeling framework based on experimental designs with at least two control samples. These are involved in a normalization and variance estimation procedure for the purpose of reducing the noise from data and scoring the true …
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COARSE CORRELATED EQUILIBRIA IN CONTINUOUS-TIME MEAN FIELD GAMES
… focus on detailed studies of specific MFG models, in which it is possible to analytically compute CCEs (or at least some of them) and compare them with more classical solution concepts. In Chapter 1 we consider MFGs driven by additive Wiener noise, with general drift and cost functions. The …