Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"light-triggered"”.
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Light-triggered release of bioactive compounds from HA/PLL multilayer films for stimulation of cells
… to be released in a controlled manner. UV light is used to trigger the release of the stored ATP with high spatio-temporal resolution. Both physico-chemical (competitive intermolecular interactions in the film) and biological aspects (cellular response and viability) are addressed in this …
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Light-triggered rupture and magnetically driven transport of lipid vesicles for controlled release and directed delivery of therapeutics
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-08-01
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Investigation of amyloid-β aggregates derived from light-triggered nitration: relevance for Alzheimer’s disease [Indagine sugli aggregati di amiloide-β derivanti dalla nitrazione indotta dalla luce: rilevanza per la malattia di Alzheimer]
La malattia di Alzheimer (AD) è caratterizzata da una complessa eterogeneità molecolare, in cui diverse forme di amiloide-β (Aβ) e modifiche post-traduzionali (PTMs) contribuiscono alla genesi di diversi percorsi di aggregazione, risposte infiammatorie e risultati clinici. Tra le PTMs, la …
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NOVEL SHAPE MEMORY AND MULTI-SHAPE MEMORY POLYMERS FOR BIOMATERIAL APPLICATIONS
… fabrication and application of an enzymatically triggered SMP, which changed its shape in response to enzymatic degradation (Chapter 2). This was achieved by combining an enzymatically stable fiber and an enzymatically vulnerable fiber. Upon degradation of the enzymatically vulnerable fiber, the …
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Novel effects in light-actuated systems based on dispersed azobenzene dyes and azopolymers
… soft polymeric materials that can be steered by light – quite literally. Through illumination in suitable settings, these materials cannot only be modulated for example in terms of softness, but they can be brought to physically deform, meaning they change shape. The directionality and amplitude …
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Self-assembly of inorganic nanoparticle amphiphiles for biomedical applications
… The hybrid vesicles were demonstrated for both light-triggered release of payload and magnetic resonance imaging. Particularly, the magnetic manipulation of vesicles to specific location can be used to enhance the photothermal effect of the vesicles in cancer imaging and therapy. Finally, we …
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Solid-state nuclear magnetic resonance of rhodopsin and its photointermediates
Photoisomerization of the membrane-bound light receptor protein rhodopsin leads<br/>to a highly energetic species called bathorhodopsin, which is stable at temperatures<br/>below 125 K. Bathorhodopsin stores about 2/3 of the absorbed photon energy but<br/>the mechanisms with which this energy is …
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Vibrational spectroscopic studies on [NiFe] hydrogenases: insights into structure and function
… range, focusing on the effect of temperature and light induced perturbations of the enrichment of certain redox species. One of the new discoveries was a light triggered conversion of the fully reduced state of the active site, Nia-SR, to the one-electron oxidized Nia-L. The light-driven Nia-SR → …
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Design strategies and application of stimuli-responsive nanoparticles for cancer diagnosis and therapy
… of nanomaterials for drug delivery via light-triggered and magnet sensitive design considerations discussed in chapter 1. The synthesized nanomaterials were extensively studied and evaluated for their chemistry and biological functions for in vitro cancer therapy and in vivo diagnosis. …
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Bypassing the Blood-Brain Barrier: Cucurbit[8]uril-based Hydrogels Towards Drug Delivery Reservoirs
… the mechanical properties on demand. Conversely, light-triggered guest moieties were introduced to spatially and temporally modulate mechanical stiffness. The third chapter builds upon this initial work through the employment of peptide functionalised hyaluronic acid (HA(CF)) hydrogels as delivery …
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Metal-cyclam based Metal-Organic Frameworks for CO₂ Chemical Transformations
… catalysts for CO₂ chemical transformations. Highlighted by their high content of active centers, large internal surface areas, tunable pore size, and versatile chemical functionalities, MOFs can serve as highly stable and reusable heterogeneous catalysts and provide a great platform to explore …