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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 56 for “"light-activated"”.
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Light-activated gene expression
… of genes by using small synthetic molecules and light. In the late 1990s, we first demonstrated this concept by using as a photo-caged β-estradiol, the hormone for the estrogen receptor (ER). This work opened the door to other light-controlled ligand/receptor systems by the Koh group and others. …
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Photoelectrochemical imaging of gold nanoparticles by light-activated electrochemistry
The concept of light-activated electrochemistry (LAE) on Si was developed as a single-wire electrode array where a light pointer created localized conductive channels on a monolithic monolayer-terminated Si electrode and allowed undertaking spatially-resolved faradaic electrochemistry on the …
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In vitro feasibility testing of floating light-activated minroelectrical stimulators
… is to use floating micro-stimulators that can be activated through optical means. As a method of energy transfer to the micro-stimulator, we propose to use a laser beam at near infrared (NIR) wavelengths. There are two main objectives in this project to test the feasibility of the main approach; …
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Development of a finite element method for light activated polymers
… changes in chemical concentration, and even light. In this thesis, we consider the photo-mechanical behavior of Light Activated Shape Memory Polymers (LASMPs), focusing on the numerical aspects. The mechanics behind LASMPS is rather abstract and cumbersome, even for simple geometries. In …
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A Comparison of Light-Activated Enzymes From Vertebrate and Invertebrate Photoreceptors
… themes of the thesis are: (1) the search for light-activated enzymes in octopus photoreceptors analogous to those found in vertebrates' photoreceptors, (2) the question of which photointermediate(s) of photoexcited rhodopsin activate bovine photoreceptor GTPase, and (3) the calcium and pH …
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Light-activated materials for singlet oxygen generation and the degradation of pollutants
The research presented in this thesis focuses on light-activated materials that may enhance the treatment of wastewater and further the understanding of wastewater treatment (WWT) technologies. Wastewater disinfection technologies and processes are categorized and discussed by groups, namely …
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Primary photoprocesses of light-activated antiviral and antitumor agents, hypericin and hypocrellin
… anti-cancer agents, whose activity depends on light which is also accompanied by photoacidification in vesicles and living cells;By complementing the techniques of time-resolved absorption spectroscopy with those of fluorescence upconversion and applying them to hypericin, hypocrellin A and B, …
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Tensile Bond Strength of Light-Activated Composite for Bonding Metal and Ceramic Brackets
Visible light-activated composite adhesives offer several advantages over conventional autopolymerizing adhesives such as extended working time, immediate ligation and easier cleanup. This study compared in vitro tensile bond strength and site of failure of a new light-activated adhesive and a …
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Design, synthesis and characterization of photocage molecules for light-activated release: Applications in polymer chemistry and phototherapeutics
… a covalently linked cargo on irradiation with a light of a particular wavelength. This characteristic of the photocages allows them to have precise spatial and temporal control over the release of substrates over time. But most of the available photocages absorbed in the UV light region and hence …
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Control of viruses in drinking water with visible light-activated TiON/PdO photocatalyst: performance dynamics associated with regeneration and activation
… a variety of pathogens when irradiated with UVA light but the UVA fraction of sun light is limited. In this research, the performance of a visible light-activated palladium-modified, nitrogen-doped titanium oxide (TiON/PdO) photocatalyst against viruses was further characterized. For initial …
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Methodologies For Attaching Polypyridyl Ligands Into Amino Acids And Synthesis And Biological Evaluation Of Novel Light Activated Peptidomimetic Cysteine Protease Inhibitors Caged By Ruii(bpy)2
… the inhibitors upon irradiation with visible light are shown, followed by cathepsin activity inhibition studies, in vitro and in cellulo. Finally, the toxicity of the complexes is evaluated in cell viability studies.</p>
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PROGETTAZIONE E SINTESI DI LIGANDI IBRIDI SIGMA-NO LIGHT-ACTIVATED A POTENZIALE ATTIVITA ANTIPROLIFERATIVA. NIH 10495 E DERIVATI: MODULAZIONE DELL ATTIVITA OPPIOIDE, SIGMA-1 ED HDAC NEL DOLORE NEUROPATICO.
… sigma1 e/o agonista sigma-2 e rilascio light-activated di NO. La duplice azione si presume che comporti un incremento sia dell’attività antiproliferativa che un azione più selettiva verso cellule tumorali over-esprimenti i recettori sigma rispetto a quelle sane con ridotta espressione …
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I. A New Ruby Glass for the Protection of Chemical Systems Sensitive to Light and High Energy Radiation. Ii. A Critical Analytical Chemical Studyof Light Activated Flavor in Milk. Iii. An X-Ray Diffraction and Electronmicroscopic Study of Positive Lead Storage Battery Plates
Made available in DSpace on 2014-12-05T19:36:01Z (GMT). No. of bitstreams: 1 0010447.pdf: 3395412 bytes, checksum: cf84b49583e8ef8fb21e52803d4d64e3 (MD5) Previous issue date: 1954
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Refinement and Applications of Light Controlled Biological Processes
… is needed. Controlling these processes using light can give us the advantage of a precise control over spacing, timing and degree of biological functions. Thus, biological processes can be turned on/off using an external light source. Multiple groups have worked on controlling cellular …
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Nanoparticles and photosensitisers; their interactions and antibacterial properties
This work reports on the coupling of light activated antimicrobial (LAA) agents with gold nanoparticles to provide new materials that displayed enhanced antimicrobial properties. A versatile and robust approach to the synthesis of gold-thiol-photosensitiser light activated antimicrobials has been …
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Synthesis And Biological Evaluation Of Nitrile-Based Inhibitors Of Cysteine Proteases Caged With Ruthenium Complexes
<p>Light activated compounds can be used as tools for understanding and solving numerous biological problems. This dissertation focuses on developing ruthenium-based photocages for caging nitrile-based cysteine protease inhibitors. Four research areas pertaining to this dissertation, i) metals in …
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Fast scanning two-photon microscopy
… two-photon microscopy coupled with the use light activated ion channels provides the basis for fast imaging and stimulation in the characterization of in vivo neural networks. A two-photon microscope capable of fast scanning using acousto-optic deflectors was designed and implemented. The …
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Photolyase: Its Damaged DNA Substrate and Amino Acid Radical Formation During Photorepair
Ultraviolet light damages genomic material by inducing the formation of covalent bonds between adjacent pyrimidines. Cis-syn cyclobutane pyrimidine dimers (CPD)constitute the most abundant primary lesion in DNA. Photolyase, a light-activated enzyme, catalytically repairs these lesions. Although …
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