Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 10 of 10 for “"levonorgestrel"”.
-
Examining swim bladder inflation failure as a toxicological endpoint in Japanese medaka (Oryzias latipes)
… to the pharmaceuticals 17α-ethinylestradiol, levonorgestrel, and diclofenac, impaired swim bladder inflation of Japanese medaka (Oryzias latipes). After exposure to individual compounds, mixture exposures to no-observed-effect concentrations of these compounds were conducted. Significant …
-
Bioresorbable Osmotic Pump for Long–term Contraception
… never been introduced. The contraceptive drug Levonorgestrel Drug microcrystals were suspended in a viscous polymer solution to achieve long-term stability. To prevent osmotic engine leakage while allowing sufficient water permeation for expansion, we developed bioresorbable semi-permeable …
-
Ultrasound Evaluation Versus Direct Measurement of Uterine Cavity Length: A Prospective Study
Levonorgestrel intrauterine devices (IUDs) have been successfully used in the adolescent population for menstrual suppression, dysmenorrhea, & contraception.1 Historically, there has been concern regarding the adequacy of the underdeveloped uterine cavity for an IUD.2, 3 Currently, there is no …
-
Determining the endometrial phenotype of women with abnormal uterine bleeding
… and incrementally increasing doses of levonorgestrel (0.1ng/ml – 500ng/ml), a widely used treatment for AUB and PR ligand, to study the progesterone responsiveness. Analysis focused on the comparison of data derived from endometrium from women with myometrial causes of AUB with the data …
-
Antiretroviral drugs differentially modulate glucocorticoid activity via the glucocorticoid receptor in vitro
… progestins medroxyprogesterone acetate (MPA) and levonorgestrel (LNG), and a GR agonist, dexamethasone (DEX) was also assessed. This study shows that (0.01 nM-10 µM) TDF, DPV and MVC do not transactivate reporter gene expression via the unliganded GR exogenously expressed in the steroid …
-
Impact of long-acting contraceptives on female genital tract cytokine profiles in a randomised controlled trial
… copper intrauterine device (IUD) or the levonorgestrel (LNG) implant. However, it remains unknown whether these contraceptives increase HIV risk relative to other forms of contraception or no contraception. This study investigated the impact of DMPA-IM, copper IUD and LNG implant on …
-
Biodegradable Polymeric Biomaterials in Different Forms for Long-acting Contraception and Drug Delivery to the Eye and Brain
… was to develop injectable ISD system containing levonorgestrel (LNG) for contraceptive effect for five months or longer after single shot that helps to reduce unintended pregnancies with high patient compliance and low cost. A series of LNG-containing ISD formulations were designed by employing …
-
Synergism between immune activators and progestogens: differential effects on gene expression and HIV-1 replication and the role of the glucocorticoid receptor
… acetate (MPA), norethisterone enanthate (NET) or levonorgestrel (LNG), the active compounds in progestogen-only hormonal contraceptives, cooperate with inflammation associated with GTIs to further elevate the risk of HIV-1 acquisition in women. Current evidence suggests MPA, LNG and NET …
-
Modulation of the progesterone receptor by progestogens, antiretroviral drugs and the glucocorticoid receptor
… norethisterone (NET), etonogestrel (ETG), levonorgestrel (LNG), medroxyprogesterone acetate (MPA) and nestorone (NES), in parallel relative to the reference progestogen promegestone (R5020). The effects of experimental conditions and progestogen metabolism on PR activity were investigated …
-
Improving Women’s Health Services by Adding Long-Acting Reversible Contraceptive Methods into Primary Care-Focused Student Health
<p> Often resulting from inconsistent contraceptive use, unintended pregnancy among young women between ages 18-24 continues to be an issue in the United States. Long-acting reversible contraceptives, including intrauterine contraceptives and the subdermal contraceptive implant, are safe, …