Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"lever press"”.
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High frequency field potentials of the cerebellar cortex
… electrode arrays while the animal performed a lever press task using the forelimb. The phase synchrony analysis shows that the high frequency oscillations recorded at multiple points across the paramedian cortex episodically synchronize immediately before and desynchronize during the lever …
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Fos induction within the ventral tegmental area following infusions of phencyclidine, MK-801, and nomifensine into the core and shell subterritories of the nucleus accumbens septi
Rats learn to lever-press for phencyclidine (PCP; NMDA channel blocker and dopamine uptake inhibitor), MK-801 (NMDA channel blocker), and nomifensine (dopamine uptake inhibitor) infusions directly into the shell but not the core subterritory of the nucleus accumbens septi (NAS). PCP, MK-801 and …
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CONDITIONED REINFORCEMENT FROM SHOCK TERMINATION.
… was presented sometimes for establishment of a lever press. In the third phase an attempt was made to bring the lever press under the discriminative stimulus control of a light. A successful response shaping effect was obtained for two of the four rats. There was no establishment of …
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Effects of Prazosin Treatment on Ethanol- and Sucrose-Seeking and Intake in P Rats
… consummatory testing phase consisted of rats bar-pressing to “pay” a specified amount up front to gain access to unlimited ethanol (or sucrose) for a 20-minute period. A 4-week appetitive testing phase examined how much the rats would bar-press for ethanol in an extinction session when no …
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Shuttlebox Self-Stimulation Behavior Following Intracerebral Microinjections of Morphine Into the Ventral Tegmental-Substantia.
… shown to increase the rate at which rats will lever-press for electrical brain stimulation as well as decrease the current intensity required for this self-stimulation. In the shuttlebox paradigm, the animal crosses from one side of the case to the other in order to turn the current on and off. …
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The Effects of Nucleus Accumbens Opiate and Adenosine Receptor Activity on Appetitive Operant Learning
… through pharmacological activation and suppression of μ-opioid and adenosine 2A receptors within the rat nucleus accumbens during the first five days of acquisition of an appetitive operant lever-pressing response. Subjects subsequently trained on the operant learning paradigm until …
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Characterizing motor control signals in the spinal cord
… in their spinal cord while they are performing lever press task they are trained in. A haptic interface and wireless neural data amplifier system simultaneously collects dynamic and neural data. Isometric force is predicted from force signal using a combination of time-frequency analysis, …
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Examining cholinergic fuction in the ventral tegmental area and dorsal hippocampus
… hippocampus (dHPC) were assessed by measuring lever pressing and quantifying the expression of immediate early gene (IEG) c-fos as a marker of neural activation. Fos expression was quantified in the VTA and in structures on which VTA activity has effect - the shell and core of the NAc, the …
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EFFECTS OF MU OPIOID RECEPTOR AGONISTS ON INTRACRANIAL SELF-STIMULATION IN THE ABSENCE AND PRESENCE OF “PAIN” IN RATS
… dimensions of pain. Specifically, pain-related depression of ICSS can model pain-related depression of behavior and mood, and drug-induced blockade of pain-related ICSS depression can serve as a measure of affective analgesia. This dissertation used mu agonists that vary in efficacy at the mu …
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The Effects of Lysine Vasopressin on Conditioned Behaviour in Rats
This thesis is concerned with lysine vasopressin's (LVP's) behavioural activity. Chapter One describes vasopressin's synthesis, secretion, metabolism, pressor, antidiuretic and putative corticotrophic functions with emphasis on behaviourally significant aspects. Chapter Two reviews behavioural data …
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Resurgence of lever pressing during a DRO challenge
… reinforced response. During Phase 1, rats’ left lever pressing was reinforced on a fixed-ratio (FR) 20 schedule while extinction was in place for right lever presses. Then, extinction was in effect for all lever presses throughout Phase 2. Phase 3 consisted of an FR 20 schedule for right lever …
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Effetto nell’auto-somministrazione dell’agonista sintetico del recettore cannabinoide CB1, WIN 55,212-2, nel modello animale di depressione della bulbectomia olfattoria (OBX)
Depression frequently coexists with substances abuse, including heavy or problematic cannabis use. To mimic this comorbidity, we combined the olfactory bulbectomy model of depression with intravenous drug self-administration procedure to verify whether depressive-like rats display higher voluntary …
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The role of locus coeruleus norepinephrine in reinforcement learning
… task where water-restricted mice must push a lever at a go tone to receive a water reward, and refrain from pushing at a no-go tone to avoid an air-puff punishment, we first explored the role of LC-NE in this behavior. Additionally, we used tones of differing intensity to modulate the …
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Neural systems involved in delay and risk assessment in the rat
… different delays (0, 10, or 20 s) between the lever-press response and reinforcer delivery. A second (inactive) lever was also present, but responding on it was never reinforced. The delays retarded learning in normal rats. AcbC lesions did not hinder learning in the absence of delays, but …