Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 305 for “"leukocyte"”.
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Leukocyte Response to Elastin-Like Polypeptide Coatings
… is still not fully understood. In this work, the leukocyte response to ELP-coated materials was investigated. In particular, ELP1 and ELP4, which differ in molecular weight and sequence length, were physically adsorbed to a polyethylene terephthalate surface (MylarTM), yielding 0.22 ± 0.13 μg/cm2 …
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On Leukocyte Recruitment in Cholestatic Liver Injury
… liver injury. In this inflammatory process, leukocyte recruitment has emerged as a key feature. Therefore, the aim of this thesis was to analyze the detailed mechanisms behind intrahepatic leukocyte accumulation and its regulation in the pathophysiology of sepsis-associated or obstructive …
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A method for the estimation of leukocyte potassium
Thesis (M.S.)--Michigan State University. Dept. of Pathology,
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Plasma and leukocyte gelatinases in health and disease
Includes bibliographical references.
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Human Leukocyte Antigen (HLA) Associations and Gulf War Illness (GWI)
… of the immune system. Many studies show Human Leukocyte Antigen (HLA) associations with autoimmune, infectious, and inflammatory diseases. Researchers have hypothesized that the multi-symptom nature of GWI may share an autoimmune component. In order to test for a potential immunological …
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Regulation of leukocyte adhesion to endothelium / by Jennifer Ruth Gamble.
Shows that the cytokine tumour necrosis factor [alpha] (TNF-[alpha]) enhances the adhesion of neutrophils to the endothelium by an action both on the neutrophil and on the endothelial cell.
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Characterisation of a novel leukocyte receptor complex-encoded receptor TARM1
… immunoreceptor encoded within the human leukocyte receptor complex and syntenic region of mouse chromosome 7, named T cell–interacting, activating receptor on myeloid cells-1 (TARM1). The transmembrane region of TARM1 contained a conserved arginine residue, consistent with association …
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On the role of mast cells in chemokine-induced leukocyte recruitment
Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. This process depends on the function of several different cells, including leukocytes, endothelial …
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Structural and molecular studies of group II leukocyte immunoglobulin-like receptors.
The Leukocyte Immunoglobulin-Like Receptors (LILRs) are a family of immunomodulatory transmembrane receptors with both activatory and inhibitory forms, and are primarily expressed on myelomonocytic cells. Group I LILRs include the well-characterised members LILRB1 and LILRB2, which bind MHC Class I …
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Electrical characterization of leukocyte activation for monitoring sepsis progression using dielectrophoresis
… characterization tool for monitoring leukocyte activation, and its application for monitoring sepsis progression. Sepsis is an uncontrolled activation of the immune system that causes an excessive inflammatory response or an impaired immunity. The unpredictable immune status makes the …
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Comparison of Leukocyte Classes Most Likely to Cause Vascular Dysfunction in Preeclampsia
Leukocytes are activated in women with preeclampsia, but the class of leukocyte most likely to cause vascular dysfunction is not known. We hypothesized that neutrophils may be the class of leukocyte most involved in causing this dysfunction because neutrophils are the most abundant of the …
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Expression of leukocyte-endothelial adhesion molecules during acute inflammation in the lung
… inflammation. In the systemic circulation, the leukocyte adhesion molecule, L-selectin, facilitates PMN adhesion to inflamed endothelium while CD11/CD18 is required for PMN emigration into extravascular tissues. An inducible endothelial ligand for CD18 is intercellular adhesion molecule-1 …
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Antimicrobial Activity of Human Leukocyte Defensin HNP-4 Against Gram-negative Bacteria
… pathogen A.a. is resistant to all of the human leukocyte α-defensins including HNP-4. Therefore, synthetic HNP-4 is not likely to be used in dental practice to prevent or treat oral disease. Resistance of A.a. to HNP-4 is not the result of a difference in LPS structure that interferes with HNP-4 …
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Integrin Modulating Factor 1 (IMF-1): A lipid that modulates leukocyte integrins
<p>Polymorphonuclear leukocytes (PMN) express a receptor of the integrin family termed complement receptor type 3 (CR3, also known as α<sub>M</sub>β<sub>2</sub>, Mac-1, Mo1, or CD11b/CD18) that functions in several cell-cell and cell-substratum adhesion events. The capacity of CR3 to mediate …
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Forces on a wall-bound leukocyte due to flowing red blood cells
… of the inflammation response, white blood cells (leukocytes) bind nearly statically to blood vessel walls before they transmigrate through the endothelium and exit the vessel. The inter-cellular interactions between the wall-adhered leukocyte and flowing red blood cells (erythrocytes) play a …
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Experimental methods by optical trapping for investigation of leukocyte cell rolling mechanics
… to investigate the mechanical behavior of the leukocyte cell membrane as it undergoes cell rolling. Membrane tethers extracted from the cell during rolling function to slow the cell down and to maintain contact with the endothelial wall. Understanding the dynamic behavior of the leukocyte …
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The Eosinophil Granular Leukocyte; Source and Target of High Mobility Group Protein B1
Eosinophils are associated with various inflammatory diseases in which they participate through the release of mediators. Eosinophils thereby function as effectors and immunoregulators and contribute to inflammation-associated disease symptoms. The high mobility group protein B1 (HMGB1) was …
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Improving Leukocyte Recovery Through Physiologically Relevant Oxygen Expansion after Hematopoietic Stem Cell Transplantation
Rapid recovery of lymphocytes post hematopoietic stem cell transplantation (HCT) is correlated with positive patient outcome in treatments of hematologic disease. Few effective clinical therapies exist to enhance lymphocyte recovery, indicating a clear unmet need. Ex vivo expansion of umbilical …
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