Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 1270 for “"lethal"”.
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Engineering resistance to maize lethal necrosis
… of an emerging maize disease, Maize lethal necrosis (MLN), and engineering resistant maize lines using an artificial microRNA (amiRNA) approach. MLN is a synergistic viral disease caused by the interaction of Maize chlorotic mottle virus (MCMV) with any maize-infecting member of the …
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Recessive lethal amber suppressors in yeast
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 1975
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Sub-lethal and lethal effects of a neonicotinoid pesticide on the development of Northern leopard frog tadpoles.
… a static-renewal experiment to monitor the lethal and sub-lethal, developmental effects in Northern leopard frog tadpoles exposed to three concentration levels (250 ng/L, 8.5 mg/L, and 85 mg/L) of imidacloprid in a laboratory setting. Survivorship was 0% by day 23 of exposure to imidacloprid …
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DEVELOPMENT OF A GENERAL LETHAL CRITERION FOR IRREVERSIBLE ELECTROPORATION
… that can judge whether tumor tissue is dead or lethal after IRE ablation. Currently, the cell lethality criterion is represented by the electric field strength, i.e., a threshold called lethal electric field threshold (LET), under the electric field, above which cells are considered dead. In …
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Effects of sublethal and lethal temperatures on plant cells
… monocotyledonous and dicotyledonous plants to sublethal and lethal temperatures. The study had four objectives: I. to compare temperatures that develop in stems and leaves of plants under flame, II. to determine the effect of heat on conduction in the phloem (of stems), III. to investigate some …
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Lethal Surveillance: Drones and the Geo-History of Modern War
… both in scope and method, my dissertation, Lethal Surveillance: Drones and the Geo-History of Modern War, examines the history of drone technology from the start of the 20th century to the present in order to understand the significance of the increasing centrality of drones to current …
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Upper lethal temperature relations of Paragnetina media Walker (Plecoptera: Perlidae)
Thesis (M.S.)--Michigan State University. Dept. of Entomology and the W.K. Kellogg Biological Station, 1968
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Less-Than-Lethal Self Defense Device with an Acoustic Element
… conception, design, and creation of a less-than-lethal self defense device with an integrated sound board to control the acoustic element. Theoretically, this device is capable of deterring potential threats without causing any serious harm or any long-term damage. When starting this project, I …
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Lethal and Mutagenic Effects of Ethyl Methanesulfonate on Bacteriophage-T4
Made available in DSpace on 2014-12-11T18:16:46Z (GMT). No. of bitstreams: 1 7105212.pdf: 3986409 bytes, checksum: 07dbef0a82c0cbba30bd459d7fdbd5d2 (MD5) Previous issue date: 1970
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Spectroscopic analysis and synthesis of nucleoside analogs for lethal mutagenesis
… deoxycytidine (KP1212), employs the mechanism of lethal mutagenesis to avoid the problem of drug resistance and use the virus's high mutation rate against it. KP1212 is incorporated into DNA by HIV reverse transcriptase (RT) but mispairs with adenine instead of guanine, increasing the rate of …
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Lethal alleles in wild population of Mus musculus (house mice)
The primary objectives of this investigation were to sample a wild population of Mus Musculus in Virginia and to report on the nature of the genetic material located at a specific point on the ninth chromosomal linkage group in this species.
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Tumor cell-immune cell interaction: A lethal two way street
We investigated the role of Fas ligand in the development of anti-tumor immunity. The LSA tumor specific cytotoxic T lymphocyte (CTL) clone, PE-9, expressed both Fas and Fas ligand. This CTL clone upregulated Fas and Fas ligand expression upon activation through the T-cell receptor and induced …
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Developing an Intervention to Promote Lethal Means Safety in Suicidal Adolescents
… Despite this uncertainty, research points to lethal means counseling with the parent of the suicidal teen as crucial and potentially the single-most powerful intervention a clinician can conduct. However, there is limited literature on how to conduct lethal means counseling and few …
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Inbreeding in Rainbow Trout (Salmo gairdneri): Analysis of Lethal Temperature Tolerence
… in relation to an altered environment (upper lethal temperature 29 C), at four levels of inbreeding. At each level of inbreeding mean time to death for inbred, female-outbred half-sib, male-outbred half-sib and outbred families were evaluated. In all cases inbreds were less resistant to lethal …
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Identification of novel synthetic lethal interactions using multiplexed CRISPR-Cas9 screening
… of this project is to identify novel synthetic lethal interactions within melanoma. Synthetic lethality describes a relationship between two genes, where loss of either of the pair is compatible with cellular viability, but simultaneous loss of both genes induces cell death. This approach can …
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Expanding cancer therapy options through genome-scale identification of synthetic lethal paralogs
Synthetic lethal therapies have the potential to expand cancer treatment options. Synthetic lethality is a form of context-dependent gene essentiality in which dual inactivation of a gene pair leads to cell death but single-gene inactivation does not affect viability. When one synthetic lethal gene …
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Cellular Responses in ESCHERICHIA COLI to Lethal and Sublethal Doses of Ozone
<p>Ozone is a major component of photochemical smog. High levels of this pollutant, sufficient to affect human health are found in many urban areas worldwide. Though limited studies in humans are supported by extensive findings from animal experiments, a difficulty in interpreting the results of …
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White fear, dehumanization and low empathy: A lethal combination for shooting biases
The question of why some individuals are racially prejudiced is one that has peaked the interests of psychologists for many years (Alport 1954; Bell, 1978; Tajfel & Forgas, 1981). To answer this complex question, scientists have had to adjust their definitions of prejudice to accommodate the …
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Enhancing cleanroom operations: From preventive equipment maintenance to lethal chemical asset tracking
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-02-04 without embargo terms
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Researching suicidal behaviours by offenders serving community based sentences: a near-lethal approach
… experiences of probation clients who made near-lethal attempts, as well as the experiences of staff managing these clients, and strategies to prevent suicide. Study 1 explored probation staff experiences of managing suicidal clients through in-depth interviews. Findings indicate that staff felt …
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