Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"left-right asymmetry"”.
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Transient CaMK-II Activation is Necessary for Left-Right Asymmetry in the Zebrafish Embryo
… are asymmetrically arranged. The development of Left-Right (LR) asymmetry is dependent on the activity of a ciliated organ known as the Kupffer’s vesicle (KV) or the embryonic node, in zebrafish and mouse, respectively. Cilia beating within the KV are essential to generate a counterclockwise flow …
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DROSOPHILA CLASS-I MYOSINS THAT CAN IMPACT LEFT-RIGHT ASYMMETRY HAVE DISTINCT ATPASE KINETICS
… myosin-1D (myo1D), that can impact Drosophila Left-Right asymmetry. De novo overexpression of either paralog in symmetric tissues results in opposing tissue rotation, dependent on the paralog. De novo overexpression of recombinant chimera proteins show that the motor domain dictates the …
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The roles of T and Tbx6 during gastrulation and determination of left/right asymmetry
… null allele of T, TWis homozygous mutants have left/right asymmetry defects. We demonstrate that left/right specific genes Cer2, Nodal, and Gdf1 are not expressed in TWis mutants and that the Notch signaling pathway, a pathway necessary for expression of left/right specific genes, is severely …
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A polarized ≥He ion source: Measuring the polarization
… of the outgoing protons, measured through the left-right asymmetry of their elastic scattering in a helium-filled polarimeter, provides the information necessary to deduce the nuclear spin polarization of the 3He ions. The polarimeter and its associated equipment are described. The results of …
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Polarization in neutron-deuteron scattering from 8 to 22 MeV
… discrimination (PSD) was used to determine the left-right asymmetry of the recoils. The experimental method depends on the fact that the PSD response of the crystal is sensitive to the direction of the recoil deuteron relative to the crystal axes. The results obtained are compared with …
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The Role for Proteoglycans in Regulating Embryonic Patterning and Morphogenesis
… I uncover a novel role for proteoglycans in left-right pattern formation. My findings resolve longstanding questions into the evolutionary conservation of Ugdh function and provide new mechanistic insights into the initiation of left-right asymmetry.
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Identifying Novel Causes of X-Linked Heterotaxy
… and abdominal organs due to errors in embryonic left-right patterning, affecting ~1 in 10,000 live births. These patients exhibit considerable phenotypic heterogeneity, with structural heart defects significantly contributing to poor outcomes. Variants in several genes can disrupt laterality, but …
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Transverse Spin Structure of the Proton Studied in Semi–inclusive DIS
… scattering (DIS). This gives rise to a left-right asymmetry in the cross-section for a transversely polarised nucleon. Another source of an azimuthal single-spin asymmetry is the so-called Sivers effect which stems from an asymmetry in the unpolarised quark distribution of a transversely …
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Left, Right, and Center: A Novel Midline Barrier Separates Asymmetric Extracellular Matrix During Intestinal Development
… directs the lengthening gut into these loops via left-right asymmetric cellular and extracellular behavior. Specifically, expansion of the extracellular matrix in the right DM and condensation of the left side drives a leftward tilt to set up the first gut loop. Vascular patterning also occurs …
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Regulation and patterning of cell differentiation and pluripotency
… Mammalian Cells Exhibit Phenotype-Specific Left-Right Asymmetry" was submitted to Proc Natl Acad Sci U S A., and it is currently under review. We attached this manuscript in appendix.