Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 21 for “"left ventricular systolic"”.
-
Hanging-Associated Left Ventricular Systolic Dysfunction
… 8 patients (2 males, 34 ± 13 year-old) showed left ventricular (LV) systolic dysfunction (mean LVEF: 34 ± 16%). Global hypokinesia was presented in one patient. Apical ballooning with sparing of the basal segments was presented in 2 patients. Basal akinesia and apical hyperkinesia was presented …
-
Studies of vascular function in patients with heart failure and either preserved or reduced left ventricular systolic function
… syndrome of heart failure have preserved left ventricular systolic function (HF-PSF). Invasive studies utilising cardiac catheterisation have demonstrated that patients with HF-PSF have abnormalities of left ventricular (LV) relaxation and filling, or LV diastolic dysfunction. As a result, …
-
Survival and prognostics of patients with heart failure and impaired left ventricular systolic and segmental function // Преживяемост и прогноза при пациенти със сърдечна недостатъчност и нарушена левокамерна систолна и сегментна функция
Цел, пациенти и методи: Група от 145 души с левокамерна дисфункция и сърдечна недостатъчност на стандартно амбулаторно лечение с изходни демографски, лабораторни и инструментални показатели са проследени проспективно за 2-години и ретроспективно за 8-годишен период с отчитане на преживяемостта и …
-
Širdies magnetinio rezonanso tomografijos vertė, prognozuojant kairiojo skilvelio miokardo kontrakcijos atsistatymą po revaskuliarizacijos /
… dose dobutamine administration) as predictors of left ventricular segmental and global functional recovery in patients with left ventricular systolic dysfunction undergoing surgical or percutaneous revascularisation. Taking into account previous studies, revascularisation of the viable myocardium …
-
Elucidating how mutations in EIF2AK4 cause pulmonary vascular disease
… pulmonary pressures which leads to right ventricular hypertrophy, and death within 1-2 years if untreated. Biallelic mutations in the stress sensing kinase, EIF2AK4 (GCN2), are the main genetic cause of PVOD. I hypothesised that loss of GCN2 may lead to a pro-inflammatory phenotype which …
-
Prevention of cancer therapy related cardiotoxicity: A Tayside Pharmaco-Epidemiology study (PROTECT-TAYSIDE study)
… of chemotherapeutic agents many patients are left with the unfortunate side effects of these drugs. Cytotoxic antibiotics such as anthracyclines and the monoclonal antibody trastuzamab are both commonly used in breast cancer and may cause irreversible cardiotoxicity, though trastuzumab-induced …
-
Heart Regeneration: An Evolutionary Tale
… (MI) in 1-day-old mice by ligating the left anterior descending coronary artery, and found that this results in extensive myocardial necrosis and systolic dysfunction. Remarkably, the neonatal mouse heart mounted a robust regenerative response, through proliferation of pre-existing …
-
The effects of right ventricular pacing in the heart failure population
… increased levels of <br/>pacing at the right ventricular apex (the conventional site) may be <br/>associated with worse outcomes in patients with impaired left ventricular <br/>systolic function. <br/>An initial observational database linkage study was performed to investigate <br/>the …
-
Secondary and Tertiary Prevention at Different Stages in the Development of Heart Failure
… with electrocardiography for the detection of left ventricular hypertrophy among patients with type 2 diabetes mellitus (T2DM) without cardiovascular disease. A total of 375 participants were recruited between 2006 and 2007. The key finding is that previously undetected structural heart disease …
-
Impact of diastolic dysfunction on physical function and body composition in maintenance hemodialysis patients
… (MHD) patients. Although metrics related to left ventricular systolic dysfunction (LVSD) such as ejection fraction (EF) are commonly used to predict adverse CV outcomes, LV diastolic dysfunction (LVDD) measures may provide better prognostic values in MHD patients because they are less …
-
Characterisation of cardiac remodeling associated with pregnancy: providing insights to peripartum cardiomyopathy
… the protein expression in the postpartum. Left ventricular systolic function was significantly reduced in late pregnancy in humans. Finally, the serum level of GDF-15 was significantly lower in PPCM patients compared to healthy controls Conclusion: We conclude that pregnancy induces cardiac …
-
The role of myocardial fibrosis and ventricular mechanical dyssynchrony in the pathogenesis and treatment of contractile myocardial dysfunction.
Structural and functional abnormalities of the left ventricle and atrium are important prognostic factors in patients with cardiovascular disease. Dysfunction of the left ventricle in heart failure exposes the left atrium to elevated pressures during diastole, which result in adverse left atrial …
-
Characterisation of the pharmacological actions in humans of multiple vasoactive enzyme inhibitors with therapeutic potential in heart failure
… (n=89) with coronary artery disease but normal left ventricular function were studied using wire myography. The vasopressor response to various neurohormones in the presence of omapatrilat, KC12615 (the active metabolite of SLV 306) and other vasoactive enzyme inhibitors is reported. 2) …
-
Effect of ivabradine, a novel I<sub>f</sub> current inhibitor, on dynamic obstruction of the left ventricular outflow tract in cats with preclinical hypertrophic cardiomyopathy: a single-dose study
… (HCM) develop dynamic obstruction of the left ventricular outflow tract and mitral regurgitation secondary to hypertrophy of the left ventricle and systolic anterior motion (SAM) of the mitral valve. This leads to an increase in left ventricular systolic pressure, and thus wall stress, …
-
Manganese-enhanced magnetic resonance imaging in cardiometabolic disorders
… P<0.001). There were no differences in left ventricular systolic and diastolic function (ejection fraction, global longitudinal strain, and peak early diastolic strain rate) between groups. In study three, we observed that myocardial manganese uptake was lower in patients with both heart …
-
The nature of cachexia in patients with heart failure and stable coronary artery disease
… 1) HF-cachexia - patients with HF, reduced left ventricular systolic function and cachexia, n=10; 2) HF-no cachexia - those with HF, reduced systolic function but no cachexia, n=20; and 3) CAD - those with CAD, no symptoms of HF and preserved systolic function, n=10. The other subject groups …
-
Cardiovascular consequences of anabolic steroid use
… (relaxation) function that suggests a stiffer left ventricle in the AS users. This imposes a greater workload on the heart and increases the risk of CV events. In study two we developed the assessment of cardiac structural assessment in AS users by adopting state-of-the-art magnetic resonance …
-
Relaxin: a new cardiovascular hormone in humans? Comparative potency and mechanisms of action
… with coronary heart disease (CHD) and normal left ventricular systolic function. We also studied the same effects in larger calibre arteries (internal mammary) and veins (saphenous) using standard organ bath techniques. The effect of relaxin in veins has not previously been described. Internal …
-
Pathophysiological role of aldosterone in cardiac remodelling after myocardial infarction
… of heart failure (HF) and/or evidence of left ventricular systolic dysfunction (LVSD) following AMI increases both in-hospital and longer-term mortality. A series of structural and functional changes occur within the heart in general and within the left ventricle (LV) in particular …
-
Heart failure and chronic obstructive pulmonary disease: common partners, common problems
… infarction (MI) complicated by heart failure, left ventricular systolic dysfunction (LVSD), or both enrolled in the Valsartan in Acute Myocardial Infarction (VALIANT) trial. COPD was an independent predictor of mortality, largely due to increased non-cardiovascular (HR 1.86 [1.43–2.42]) and …
Page 1 of 2