Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"left ventricular dysfunction"”.
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Nitrates and Left Ventricular Dysfunction
… of nitrate therapy in patients with evidence of left ventricular (LV) dysfunction after acute myocardial infarction (AMI) already treated with standard heart failure (HF) therapy. Paper I. In a randomized, double-blind, placebo controlled trial, we evaluated the effects of a 60 mg dose of …
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Genetically-programmed suicide of adrenergic cells in the mouse leads to severe left ventricular dysfunction, impaired weight gain, and symptoms of neurological dysfunction
… show that loss of Pnmt cells results in severe left ventricular dysfunction that progressively worsens with age. These mice exhibit severely reduced cardiac output and ejection fraction due to decreased LV contractility and bradycardia at rest. Surprisingly, these mice appear to have a normal …
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Effects of exercise training on left ventricular function and exercise capacity in patients with coronary artery disease and varying degrees of left ventricular dysfunction
… patients may have developed chronic asymptomatic left ventricular dysfunction and/or residual myocardial ischaemia, and could become potential candidates for cardiac rehabilitation if exercise training could induce physiological benefits without further deteriorating their condition. Over the last …
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Neurohormonal and inflammatory markers in valvular heart disease
… After the development of symptoms or left ventricular dysfunction, mortality is high without surgical intervention. Currently there is no known medical therapy that influences disease progression or clinical outcome. While the development of symptoms or left ventricular dysfunction are …
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Širdies magnetinio rezonanso tomografijos vertė, prognozuojant kairiojo skilvelio miokardo kontrakcijos atsistatymą po revaskuliarizacijos /
… dose dobutamine administration) as predictors of left ventricular segmental and global functional recovery in patients with left ventricular systolic dysfunction undergoing surgical or percutaneous revascularisation. Taking into account previous studies, revascularisation of the viable myocardium …
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An evaluation of cardiac services in four hospitals in Lancashire for patients with ischaemic heart disease
… consensus); 3) 52% of patients diagnosed with Left Ventricular Dysfunction by their OP at six-months post MI had not received thrombolytic therapy. It can be concluded from the sample that the total study will reveal many instances where the standard of cardiac care can be greatly improved, …
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Magnetic resonance imaging of the right ventricle in human pulmonary hypertension
… illness which results in progressive right ventricular (RV) failure and early death. RV function determines survival in all patients with PH but it is difficult to measure accurately using existing clinical techniques. The choice and design of the experiments in this thesis was driven by a …
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Quality of Life, Hope, Social Support, and Self-Care in Heart Failure Patients
… clinics. Quality of Life was measured using the Left Ventricular Dysfunction Questionnaire (LVD-36), Hope was measured using the Herth Hope Index (HUI), Social Support was measured using the Medical Outcomes Study – Social Support Survey (MOS – SSS), and Self-Care was measured using the Self-Care …
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A sequential evaluation of left ventricular function in asymptomatic and symptomatic patients with chronic severe aortic regurgitation
… the unpredictable development of pre-symptomatic left ventricular (LV) dysfunction as a result of prolonged volume overload has resulted in numerous reports attempting to formulate a risk profile for these patients. Although aortic root and LV cineangiography have been the "gold standard" for …
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ASSOCIATION BETWEEN ATRIAL SIZE AND CEREBROVASCULAR EVENTS: A RETROSPECTIVE, COHORT STUDY
Background: Left atrial enlargement (LAE) is a cardiac structural abnormality linked to cardiovascular risk, including stroke. However, its independent prognostic role in patients without atrial fibrillation (AF) remains unclear. We carried out a prospective cohort study to assess the association …
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The role of myocardial fibrosis and ventricular mechanical dyssynchrony in the pathogenesis and treatment of contractile myocardial dysfunction.
Structural and functional abnormalities of the left ventricle and atrium are important prognostic factors in patients with cardiovascular disease. Dysfunction of the left ventricle in heart failure exposes the left atrium to elevated pressures during diastole, which result in adverse left atrial …
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Type-5 Phosphodiesterase Inhibition in the Prevention of Doxorubicin Cardiomyopathy
… Bcl-2 was analyzed by Western blot. Left ventricular function was measured in Langendorff mode. Electrocardiographical analysis measured changes indicative of doxorubicin cardiotoxicity (ST-prolongation). In vitro studies using adult ventricular cardiomyocytes were exposed to …
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The acute effects of two different training models on markers of inflammatory activation and skeletal muscle injury in patients with chronic heart failure
… IL-6) have been related to increased severity of left ventricular dysfunction, the activation of the sympathetic and renin-angiotensin systems and the catabolism of skeletal muscle. Although exercise training is important in the management of HF, acute bouts of exercise may lead to increases in …
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Assessment of myocardial viability using magnetic resonance imaging
… microembolization causes long-term, regional left ventricular dysfunction and that even small microemboli, which may escape the distal protective devices, influence cardiac function. Study II demonstrated that infarct quantification with a 2D-PSIR and a 3D-IR sequence shows good agreement in …
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The electrophysiology of the atrioventricular node in normal and failing rabbit hearts
… have observed abnormal delay in atrioventricular (AV) conduction in a rabbit model of left ventricular dysfunction (LVD) due to apical myocardial infarction. In this model, AV conduction time increased with increasing pacing rates, suggesting the most likely site of delay is the AV …
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Characterisation of the pharmacological actions in humans of multiple vasoactive enzyme inhibitors with therapeutic potential in heart failure
… (n=89) with coronary artery disease but normal left ventricular function were studied using wire myography. The vasopressor response to various neurohormones in the presence of omapatrilat, KC12615 (the active metabolite of SLV 306) and other vasoactive enzyme inhibitors is reported. 2) …
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Dynamic 129Xe Magnetic Resonance Spectroscopy: Development and Application in Diverse Cardiopulmonary Diseases
… obstructive pulmonary disease (COPD), IPF, left heart failure (LHF), and pulmonary arterial hypertension (PAH). The chosen cohorts provide two forms of chronic lung disease (IPF, COPD) and two forms of PH (LHF, PAH) that have different impedance locations with respect to the pulmonary …