Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 81 for “"learning memory"”.
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The role of the CB1 receptor in learning, memory and anxiety-like behaviors
… display deficits in extinction during reversal learning. In the Light-Dark Box and Suok tasks, the CB1-/- mice demonstrated greater anxiety-like behaviors relative the CB1+/+ mice. No differences were observed in the Open-Field task, suggesting that the observed behavioral differences may be …
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The role of the CB1 receptor in learning, memory and anxiety-like behaviors
… display deficits in extinction during reversal learning. In the Light-Dark Box and Suok tasks, the CB1-/- mice demonstrated greater anxiety-like behaviors relative the CB1+/+ mice. No differences were observed in the Open-Field task, suggesting that the observed behavioral differences may be …
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Neural correlates of motor learning/memory in primary motor cortex of macaque monkeys
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1998.
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Multifractal Complexity of Hippocampal Memory Processing
The hippocampus has long been associated with learning and memory occurring as reverberating activity patterns within ensembles of hippocampal neurons. Fractals, omnipresent in biological and physical systems, often manifest when systems are iterative or reverberatory, and consequently are …
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Decoding Gating Properties of the Pannexin1 Channel: ATP Release and pH Sensitivity and the Potential Role in Health and Disease
… in important physiological processes including learning, memory and sensory function. In sensory systems, ATP release and purinergic signaling is considered the most important function of Panx1. Here, the function in the olfactory epithelium was investigated using Panx1 knock out mice. …
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An exploratory study of neuropsychological impairment, driving performance, and sleepiness in obstructive sleep apnoea and chronic obstructive pulmonary disease
… on tasks measuring reaction time, concentration, learning, memory, and driving ability have been observed. These deficits result in a higher risk of accidental injury for people who are diagnosed with such disorders. In patients with OSA, impaired performance on these measures may reflect the …
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Experience-Dependent Plasticity in the Mushroom Bodies of the Honey Bee Brain
… a region of the insect brain implicated in learning, memory, and multimodal sensory integration. To study this phenomenon, I have developed an assay to control foraging experience in the lab while incorporating the effects of social and environmental conditions on the brain. Using this …
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Targeting Cognitive Impairment in Parkinson’s Disease: Novel Pharmacological and Non- Pharmacological Approaches
… and involve dysfunction in domains such as learning, memory, response inhibition, visuospatial function and executive function. Unfortunately, current treatments for CI in PD provide variable symptomatic relief but do nothing to alter disease progression. To this end, the aim of this thesis …
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An analysis of morphological changes in visual cortical neurons after knocking down scaffolding proteins of glutamate receptors
… important implication in synaptic development, learning, memory, and neuronal disorders. Previous studies have suggested that two membrane-associated guanylate kinase (MAGUK) family scaffolding proteins, SAP102 and PSD-95, are involved in the switch from predominance of NMDA receptors rich in …
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Physiological High-Frequency Oscillations in Scalp EEGs Change During Brain Maturation
… then, physiological HFOs have been implicated in learning, memory and motor function, while epileptic HFOs have been associated with epileptogenic tissue. Many studies have shown that HFO activity correlates with seizure frequency, severity, and surgical outcomes. However, distinguishing …
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EXPERIENTIAL NEGATIVE SYMPTOMS IN YOUNG ADULTS ENDORSING PSYCHOTIC-LIKE EXPERIENCES
… we examined the potential influence of episodic memory performance factors on the relationship between MAP symptoms and PLEs/PLEDs. Collectively, this project highlights the importance of including negative symptoms (i.e., MAP deficits) and/or cognitive performance (i.e., associative/relational …
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The Effects Of Courtship And Pairing Behavior On The Nonapeptide And Noradrenergic Systems Of Adult Male And Female Zebra Finches
… neural circuits, including those involved in learning, memory, motivation, and attention. Two neurotransmitter pathways highly involved in these neural circuits are norepinephrine (NE) and the nonapeptides, vasopressin (AVP) and oxytocin (OT). There is extensive research implicating a role for …
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The Extracellular Domains of the AMPA, Kainate, and Orphan Delta Receptor Regulate Channel Gating in Distinct Ways
… and neurological functions such as learning, memory, behavior, cognition, and motor coordination. Mutations in these channels are linked to various disorders including autism, ataxia, and epilepsy, making them compelling pharmacological targets. Within this family, the …
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Neuropsychological subgroups of dementia of the Alzheimer's type
… groups overall showed greatest deficits in memory functions. The most severely impaired group was characterized by dramatically poorer language skills. Mean ages of the DAT groups was similar so that age alone did not appear to contribute to cluster differences. Moreover, information …
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Spatially restricted proteomic mapping of excitatory and inhibitory post-synaptic termini through enzymatic labeling
… face in characterizing precise mechanisms of learning, memory, and cognitive decline will require the ability to finely dissect neurons and synapses into their own distinct subtypes, and understand them from a detailed molecular standpoint. The goal of this thesis is to introduce a novel …
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Identification and characterization of components of rab-6-mediated trafficking in caenorhabditus elegans
… plasticity and influences processes involved in learning, memory formation, and motor control (Greger and Esteban, 2007; Shepherd and Huganir, 2007). In Caenorhabditis elegans, recycling of the AMPA receptor subunit GLR-1 has been demonstrated to be one method by which synaptic signaling …
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A Multi-method Analysis of Intersensory Perception of Social Information in Children and Adolescents with Autism Spectrum Disorder
… impacts the cascading cycle of perception, learning, memory, attention and so on and contributes to core sensory and social-communication impairments associated with Autism Spectrum Disorder.
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Behavioural and neural dynamics of category learning across the menstrual cycle
… account of menstrual cycle effects on category learning – a core cognitive process that requires careful coordination of learning, memory and attention. Study 1 outlines a novel method for studying cognition across the menstrual cycle, and leverages it to demonstrate that category learning …
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Consequences and Prevention of Elevated Circulating Tyrosine during Nitisinone Therapy in Alkaptonuria.
… treatment had no detrimental effect on learning, memory or motor function in young AKU or wild type mice. The thesis also includes new data from mouse dosing studies concerning the correlation between plasma HGA and ochronotic pigmentation and reveals that plasma HGA must be lowered to a …
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