Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"leakiness"”.
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Characterization and reduction of leakiness in melamine formaldehyde microcapsules
This thesis is concerned with tackling three major challenges of melamine formaldehyde (MF) microcapsules for delivering of core materials: reducing the formaldehyde content in the formulation, modulate the mechanical properties and reducing the leakage of the core material through the …
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Modulating tissue mechanics to increase oxygen delivery to tumors
… of perfused vessels supplying tumors. Excessive leakiness slows blood flow partly by reducing the intravascular pressure drop. Strategies to repair leakiness towards decreasing hypoxia exist, so I developed approaches for overcoming compression. In order to understand the origin of vessel …
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Energetics of maize C4 physiology under light limiting conditions
… CCM generally decreases, causing an increase in leakiness, (Φ), the ratio of CO2 retrodiffusing from the BS relative to C4 carboxylation processes. This increase in Φ had been theoretically associated with a decrease in biochemical operating efficiency (expressed as ATP cost of gross …
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Physiological studies on bacterial fermentations using multi-parameter flow cytometry
… 2006), there was extensive evidence of promoter leakiness. Fab production was usually synonymous with cellular breakdown, however, a strategy based on simultaneous feeding and induction, before the exhaustion of the primary carbon source, yielded the highest concentration of Fab, 105 mg.L-1, with …
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Mechanisms of methylenedianiline toxicity to rat biliary epithelial cells
… between BEC in vitro showed both increased “leakiness” and decreased ion selectivity following exposure to bile from DAPM-treaded rats (DAPM-Bile). Furthermore, this model indicated that BEC ATP levels and mitochondrial membrane potentials were altered prior to any changes in tight junction …
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Cancer Associated Fibroblast Derived Angiogenic Factor Mfap5 In Ovarian Cancer Progression
… via the reduction of intratumoral microvessel leakiness.</p> <p>To conclude, our results demonstrated the important roles of MFAP5 in promoting ovarian tumor progression and the potential of targeting stromal MFAP5 as a novel therapeutic approach for ovarian cancer.</p>
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Effects of Acute Alcohol Exposure on Post Burn Intestinal Immunity: Role of IL-23
… demonstrated increased intestinal tissue damage, leakiness and bacterial translocation as well as intestinal T lymphocyte suppression following EtOH intoxication and burn injury.</p> <p>Th17 cells are implicated in gut homeostasis and in the containment of gut pathogens. We investigated the …
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Tools for improving and understanding microbial performance in biorenewable applications
… to phosphoethanolamine somewhat improved the leakiness and fluidity. Therefore, small alterations in the phospholipid composition could be helpful in creating more robust membranes.</p>
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Of engineers, rationalities, and rule: An ethnography of neoliberal reform in an urban water utility in South India
… Water, as the classic commons, demonstrated the leakiness of abstract orders, and provided an insightful lens into neoliberal governance by challenging projects of commodification/privatization as well as bureaucratic channels of state sovereignty.
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Engineering the tumor microenvironment using microfluidics : effects of cell-cell interactions and endothelial barrier function on tumor cell intravasation
… require a leaky endothelium? To induce vessel leakiness we perturb the barrier using biochemical factors, endothelial cells with low expression of basement membrane proteins and signaling with macrophages. Under all these conditions, tumor cell intravasation rates increased and we confirmed …
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Development of a modelling framework for integrated catchment flood risk management
… storage utilisation by allowing a degree of “leakiness” to enable drain-down between storms. An unanticipated result was that some configurations of measures could synchronise previously asynchronous subcatchment flood waves and have a detrimental effect on the flood risk. The framework shows …
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Role of the small subunit of Rubisco in the green algal phylogeny and Carbon Concentrating Mechanism expression
… reflect the strength of any CCM and pyrenoid leakiness, whereas Rubisco in extant land plants reflects more recent selective pressures associated with the terrestrial atmospheric environment. This research also provides evidence for diversity of CCM expression in two closely related genera …
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Topological chaos and chaotic mixing of viscous flows
… describe the stirring in the flow, invariance or leakiness of the Almost Invariant Sets (AIS) playing the role of ghost rods is found to be in a direct relationship with the rate of homogenization of a scalar. The mixing caused by these AIS and the variations of their structure are explained from …
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The Binding Properties and Functional Consequences of Ryr2-Cam Interaction
… RyR2 and recapitulate this arrhythmogenic RyR2 leakiness by unzipping N- and central-domains. In this study fluorescently-labeled DPc10, FKBP12.6, and CaM were used to characterize the binding properties of DPc10 to RyR2 in permeabilized rat ventricular myocytes. DPc10 access to its binding site …
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Understanding and engineering photoresponses in Arabidopsis thaliana
… benthamiana leaves but displays significant leakiness and requires further development before its uses can be developed upon. Additionally further development is required in order to better engineer the system for the production of stable transgenic lines in Arabidopsis. The studies presented …
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Characterising natural genetic variation in dynamic photosynthesis and photoprotection in sorghum
… of high-light treatments on bundle sheath leakiness– an indicator of loss-of coordination between cell types. The results suggest that the C<sub>4</sub> photosynthetic apparatus is robust under both fluctuating and steady-state high light conditions and that NPQ capacity may partially …
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Analysis of the role of the mineralocorticoid receptor in renal principal cell sodium reabsorption in vivo
… in most of the renal principal cells, but leakiness of the fusion protein in the papilla region of the kidney. To identify aldosterone-regulated genes potentially involved in the control of ENaC-mediated renal sodium reabsorption, gene expression profiling using microarrays was performed on …
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Intracellular triggering of inflammation by the extracellular bacterium Pseudomonas aeruginosa
… elucidate this finding, we investigated the leakiness of the pore formed by the T3SS in the host cell membrane. No flux of ions or small molecules could be detected in the host cell membrane following infection. However, host-membrane repair mechanisms were triggered, which could be detected …
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On the Structure and Function of Multidrug Efflux Pumps
… protein (MacA), which leads to a seeming leakiness of the assembly, and (2) the fact that substrate has to pass through a narrow aperture in the membrane-fusion protein for extrusion, it is rather surprising that MacB was previously shown to transport an entire toxin. An experimental …
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Expanding the molecular tools for the microalgae Chlorella vulgaris and Phaeodactylum tricornutum
… terminator or intron did not alleviate the leakiness. However, the P<sub>*AP1*</sub> was successfully switched off when high concentrations of phosphate were supplied in the media. The P<sub>*METE*</sub> was shown to drive strong expression and can be modulated by varying the concentration …
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