Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"layer 6"”.
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Layer specific differences in the mouse auditory corticocollicular system
… streams emanating from auditory cortical layer 5 and layer 6 that influence the auditory midbrain. To examine the functional properties of neurons in these two layers that project to the midbrain, we performed three sets of experiments. First, to determine whether these projections have …
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The role of cortical layer six in the perception and laminar representation of sensory change
… expected and actual sensory input, and the layered architecture of neocortex is presumably central to this computation. In this thesis, I examine the role of laminar differences, and specifically the role of layer 6 (L6) in the encoding and perception of stimuli that deviate from previous …
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Causal control of the thalamic reticular nucleus using optogenetic and novel chemogenetic approaches
… firing to bursting in thalamic relay neurons or layer 6 of neocortex. The temporal dynamics of these inputs, and their spatial organization, can drive different types of firing behavior in TRN. Layer 6 cells form strong synapses in the TRN and even sparse activity in this layer would be predicted …
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Investigating the role of thalamic activity in visual cortical plasticity
… activity but not LTP onto the classic input to layer 4 of the visual cortex. Such differences may be clarified by analyzing the dorsal lateral geniculate nucleus (dLGN) of the thalamus, which is the primary source of visual information for the cortex. In the following sections, we test the …
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Selective Neuronal Vulnerability in Neocortices from Patients with C9ORF72-related Neurodegeneration
… 3). Upper motor neurons (herein called L5 ETs: layer 5 extratelencephalic-projecting excitatory neurons) were expected to display pathology in c9HRE and served as a positive control. Other vulnerable neuronal populations were identified by examining neurons with similar transcriptomic responses …
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Molecular and Functional Characterization of Pyramidal Cell Types in the Frontal Cortex of Mouse Brain
… These include corticocortical neurons in upper layer 2 of neocortex defined by genes Ntf3, Pdyn and Wfs1, corticostriatal neurons in layer 5a of lateral cortex expressing Etv1 and corticothalamic neurons in layer 6 of neocortex defined by Ntsr1 and Syt6. We generated translation profiles of …