Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"lateral hypothalamus"”.
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Recovery of specific deficits following unilateral lesions of the lateral hypothalamus in rats
Digitized by Kansas Correctional Industries
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The lateral hypothalamus and energy balance : facilitation and inhibition of perifornical self-stimulation by long- and short-term metabolic signals
… reinforcers such as food. The lateral hypothalamus (LH) is considered a particularly good site for obtaining vigorous self-stimulation in rats. There is evidence that chronic food restriction enhances the reward value of LH electrical stimulation when the electrode is positioned …
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The Role of Lateral Hypothalamic Neuropeptides in Drug Addiction and Feeding Behavior
… metabolism on reward related behaviors such as lateral hypothalamus self-stimulation (LHSS). The lateral hypothalamus (LH) is a brain structure with prominent roles in feeding, arousal and reward. Recent studies have found that melanin concentrating hormone (MCH), orexin A and orexin B are …
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Investigating the influence of LH-projecting BLA neurons upon motivated behavioral responding and appetitive learning
… of therapies. Two neural regions, the basolateral amygdala (BLA) and lateral hypothalamus (LH), are both implicated in reward processing (Adamantidis et al., 2007; Anand and Brobeck, 1951; Brobeck, 1946; Gutierrez et al., 2011; Hoebel and Teitelbaum, 1962; Kempadoo et al., 2013; Margules …
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Lateral hypothalamic control of motivated behaviors through the midbrain dopamine system
The lateral hypothalamus and ventral tegmental area are two brain regions that have long been known to be involved in processing reward and the control of feeding behaviors. We continue work in this area by identifying the functional connectivity between these two regions, providing evidence that …
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Satiety induced by neuropeptide FF and gastrin in birds
… was increased c-Fos immunoreactivity in the lateral hypothalamus (LH), paraventricular nucleus (PVN), arcuate nucleus, nucleus of the solitary tract, and area postrema at 1 h post-injection. Although a variety of genes were measured in those activated nuclei, there were only differences in …
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Neurochemical and functional characterisation of the Melanin-concentrating hormone system in the rat brain
… immunohistochemistry within the rat hypothalamus. Of special interest is the neuroanatomical identification of other hypothalamic neuropeptides that are co-distributed with MCHR-1. A second part of this study deals with the examination of neuronal activation patterns after …
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Preliminary characterisation of the neuropeptide melanin concentrating hormone in humans
… expressed centrally in the zona incerta and lateral hypothalamus. Evidence from rodent studies implicates hypothalamic MCH in the modulation of varied and diverse physiological functions most notably in energy homeostasis but also emerging as a candidate mediator in reproductive activities. …
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Neuromedin U Acts via the Paraventricular Nucleus of the Hypothalamus and the Dorsal Raphe Nucleus to Regulate Motivation for High-Fat Food
… signaling in the paraventricular nucleus of the hypothalamus (PVN), NMU has also been found in other brain regions involved in both feeding behavior and motivation. We investigate the effects of NMU on motivation for food and food intake, and identify the brain regions mediating these effects. …
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Effects of constitutive and acute Connexin 36 deficiency on brain-wide susceptibility to PTZ-induced neuronal hyperactivity
… which is implicated in human epilepsy, and the lateral hypothalamus, which has been underexplored. We also found that PTZ-induced neuronal hyperactivity resulted in a rapid reduction of Cx36 protein levels within. 30 minutes and one-hour exposure to 20 mM PTZ significantly reduced the expression …
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Food intake in birds: hypothalamic mechanisms
… appetite-associated regions including the lateral hypothalamus, paraventricular nucleus, ventromedial hypothalamus, dorsomedial nucleus, and arcuate nucleus and I measured gene expression of various appetite-associated factors in the whole hypothalamus and individual nuclei. These data …
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Hypothalamic Circuits In The Control of Feeding and Emotional Behaviors
… by complex neural circuitry in the brain. The hypothalamus is a critical center controlling feeding and motivated behaviors. We found that targeted photostimulation of projections from the lateral hypothalamus (LH) to the paraventricular hypothalamus (PVH) in mice elicited voracious feeding and …
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Hypothalamic Circuits Mediating Consumption and Anxiety
… demonstrate that GABAergic eating neurons in the lateral hypothalamus (LH) inhibit GABAergic anxiety neurons in the basal forebrain (BF). Activating this circuit causes feeding and reduces anxiety; fiber photometry shows LH neurons are active both during food approach and food consumption, but BF …
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Factors controlling the expression of central progesterone receptors
… density occurring in the preoptic area and the lateral hypothalamus. The distribution of cells containing PR-ir demonstrated a similar pattern in both laying and brooding birds. The number of PR-ir cells was consistently lower in brooding birds than in laying. The intensity of PR expression was …
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Hypothalamic Regulation of Food Intake in Obese and Anorexic Avian Models
… homeostatic regulation of appetite is the hypothalamus, and hence this dissertation was focused on understanding how the hypothalamus is different between LWS and HWS lines. Experiments 1 and 2 were performed as follows: whole hypothalamus as well as individual hypothalamic nuclei, …
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Hypothalamic Mechanisms of Food Intake in Birds
… and neurotransmitter signaling in the hypothalamus. External factors, such as high ambient temperature (HAT), can indirectly affect appetite regulation through other neuroendocrine systems such as the hypothalamo-pituitary-adrenal (HPA) axis. Understanding the physiological responses to …
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The interactive and individual effects of orexin A and neurotensin in the brain on spontaneous physical activity.
… orexin A into the dorsal rostral portion of the lateral hypothalamus. We have previously observed an acute increase in spontaneous physical activity as well as food intake following injection of orexin A into this area. The acute effect is also observed with bicuculline-mediated stimulation of …
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Arc expression in the parabrachial nucleus following taste stimulation
… Arc expression was denser in the lateral PbN than the medial PbN. In mice that received two temporally separated taste stimulations, each stimulation time-point showed a distinct population of Arc-expressing neurons, with only a small population (10 – 18 %) of neurons responding to …
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Mechanisms of hypothalamic regulation of food intake in birds
… central and peripheral neural signaling. The hypothalamus is responsible for integrating and processing these signals and thus is regarded as the regulatory center for balancing energy homeostasis. Eating disorders, such as compulsive eating behavior associated with obesity, and anorexia, are …