Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"latency reversal agents"”.
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Platinum and palladium complexes as human immunodeficiency virus latency reversal agents
… made to develop vaccines and chemotherapeutic agents. However, an effective vaccine remains elusive, and existing HIV/AIDS medications do not lead to a cure. Antiretroviral therapy (ART) has been instrumental in suppressing the virus, but it cannot completely eradicate HIV due to its …
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The impact of heptose phosphates on HIV latency and human immune responses
Use of HIV-specific antiretroviral therapeutic agents (ARTs) achieves total control of viremia and prevents progression of HIV to AIDS, but they are not a cure. Shock-and-kill therapy aims to use HIV latency reversal agents to promote clearance of HIV infected CD4 T-cells that make up the HIV …
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Therapeutic Uses of Broadly Neutralizing Anti-HIV-1 Antibodies in Humanized Mice
… hu-mice, I show that when administered as single agents, recently discovered broadly neutralizing monoclonal antibodies (bNAbs) induce selective pressure at restricted viral epitopes. This causes a transient drop in viremia and the rapid emergence of viral escape mutants. When bNAbs are …