Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"late-stage functionalisation"”.
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Planning And Interpretation Of Late Stage Functionalisation Reactions
… drug candidates in a fast and efficient manner. Late stage functionalisation (LSF) is poised to accelerate the process by making chemical synthesis modular so most of the molecules are assembled via standard protocols. Predicting the major reaction site is not straightforward due to multitude of …
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A Promiscuous Path to Novel Guanidines: Arginine-Modifying Enzymes as Key Synthetic Players
… conversion and demonstrating its utility for late-stage functionalisation of complex natural products and drugs (e.g., the pentapeptide opiorphin). These findings highlight SznE's potential for biocatalysis, engineering, and industrial applications. The 2nd Section demonstrates the …
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Studies in iridium and manganese catalysis in C-H activation and reductive transformations
… has proven a useful means of heteroarene functionalisation, due to its ability to produce highly versatile aryl organoboronate intermediates. The quinoline nucleus is a ubiquitous, strategic target, given its role as a key scaffold in a plethora of synthetic and naturally occurring …