Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"laser scanning cytometry"”.
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Discovery of new biomarkers of mild cognitive impairment and Alzheimer's disease risk in buccal cells using laser scanning cytometry
… with MCI or AD was therefore tested using laser scanning cytometry (LSC). LSC combines the principles of flow cytometry, quantitative imaging and immunohistochemistry with high-content, multi-color fluorescence analysis, and can be used to identify specific cells in a heterogeneous …
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Entwicklung und Anwendung eines Expressionsklonierungssystems in primären Kardiomyozyten - Identifizierung von Translin als neuem Target der Herzinsuffizienz
… the hypertrophic process. A new system based on laser scanning cytometry was developed as read out. We managed to screen hundreds of cDNAs leading to the discovery of the new target protein Translin. Its overexpression caused the hypertrophic elongation of cardiomyocytes in vitro and could be …
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A Preclinical Model of Ionizing Radiation and TNF-alpha Gene Therapy for Cancer
… medium (CM) from 1 x 105 cells. Using Laser Scanning Cytometry, we confirmed that both P55 and P75 receptors for TNF-α were present on the C6 cell membrane. P55 receptors are expressed at significantly higher levels than P75 receptors. The expressed TNF-α alone did not inhibit growth of …
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Investigation of T cell signalling events regulating immunity and tolerance in vivo
… the population. A relatively new technology, laser scanning cytometry (LSC), offers an attractive means of investigating such responses, as it essentially marries the quantitative capabilities of flow cytometric analysis of cells in suspension with the ability to analyse spatially the …
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Regenerationspotenzial CD133+-hämatopoetischer Progenitorzellen der humanen Nabelschnur beim Nierendefekt im Mausmodell
Eine Schädigung des renalen Tubulusgewebes ist in den meisten Fällen irreversibel. Persistierender Abbau oder chronische inflammatorische Prozesse führen letztendlich zum Nierenversagen. Bisher sind die therapeutischen Optionen auf eine Dialyse beziehungsweise Organtransplantation begrenzt. In den …