Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"lamotrigine"”.
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Health technology assessment for levetiracetam in the treatment of newly diagnosed epilepsy in the South African Public Health Sector
… drugs in this analysis which are levetiracetam, lamotrigine, carbamazepine, phenytoin and valproate. The current first-line epilepsy treatment in South Africa is lamotrigine, phenytoin or carbamazepine. Levetiracetam is under consideration for use as a first-line treatment due to the reported …
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Characterization and application of human pluripotent stem cell-derived neurons to evaluate the risk of developmental neurotoxicity with antiepileptic drugs in vitro
… phenobarbital, valproic acid, carbamazepine and lamotrigine, on cell viability, cell cycle and differentiation of TERA2.cl.SP-12 into neurons was studied. All AEDs tested reduced differentiating stem cell viability. Valproic acid and carbamazepine increased apoptosis and reduced cell …
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Pharmacist input into patients' self-reporting of adverse drug reactions.
… nefazodone, citalopram, moclobemide, gabapentin, lamotrigine and topiramate from 79 participating medical practices in Grampian during January-March 1997. The overall response rates were 44.6% (n=207) for the pilot study and 36.3% (n=837) for the main study. The most frequently reported symptoms …
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The Impact of Cognition on Treatment Adherence in Comorbid Bipolar Disorder and Cocaine Dependence
… double-blind, placebo controlled trial of lamotrigine. Baseline performance on the Stroop Color and Word Test and the Rey Auditory Verbal Learning Test were examined for their effect on retention, appointment attendance, medication adherence, and return of medication bottles. Participants …
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Health technology assessment in maternal and perinatal medicine: delphi survey of practice, systematic reviews of evidence and meta analyses
… 0.26 to 0.55) in pregnant women with epilepsy on lamotrigine dosage based on serum levels compared to 0.73 (95% CI 0.56 to 0.86) in those managed by clinical features only. The abstracts of 19,500 citations were reviewed to identify the studies of accuracy of tests in pre eclampsia including …
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Onsite Remediation of Pharmaceuticals and Personal Care Products in Domestic Wastewater using Alternative Systems Including Constructed Wetlands
… of persistent pharmaceuticals carbamazepine and lamotrigine (>85% and >95%, respectively).
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NOVEL THERAPEUTIC APPROACHES EMERGING FROM HCN CHANNELS STRUCTURAL AND FUNCTIONAL STUDIES
… mice, which is further amplified following lamotrigine administration. Sleep architecture is also disrupted in these animals, suggesting that HCN1 dysfunction impacts broader aspects of brain function beyond seizure susceptibility. Together, these findings provide a comprehensive …
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The newer anticonvulsants in the treatment of generalised anxiety disorder: a systematic review and meta-analysis
… newer anticonvulsants (felbamate, gabapentin, lamotrigine, levetiracetam, oxcarbazepine, pregabalin, tiagabine, topiramate and zonisamide) were investigated as they were considered to have a more benign side effect profile and fewer drug interactions than older anticonvulsants. This study is a …
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Characterising the functional homology of central nervous system drug targets in larval zebrafish (Danio rerio)
… compounds: three anticonvulsants (carbamazepine, lamotrigine, gabapentin), three antidepressants (venlafaxine, escitalopram, trazodone), and three antipsychotics (aripiprazole, clozapine, risperidone). Chapter 1 reviews the occurrence, mechanisms of action, and environmental relevance of …
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Modulation der synaptischen Langzeitplaztizität durch Lithium und Lamotrigin
In dieser Arbeit wurde die Modulation synaptischer Plastizität in CA1- <br>Pyramidenzellen durch die beiden Medikamente Lithium und Lamotrigin mit <br>Ganzzell-Ableitung in der Patch-Clamp Technik untersucht. Synaptische Plastizität wird als ein zelluläres Korrelat für Lernen und Gedächtnis …