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Showing 1 to 2 of 2 for “"laminin gamma 1 gene"”.

  1. Role of Laminin gamma 1 in Cortical Development

    <p>Laminins are a major component of basement membranes, including those in the central nervous system (CNS). To explore the role of laminin γ1, a subunit common to all laminins found within the CNS, we developed a murine model in which laminin γ1 is conditionally disrupted in the nervous system. …

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  2. Role of Laminins in the Development of the Peripheral Nervous System

    <p>To investigate the function of laminins in peripheral nerve development, the laminin γ1 gene was specifically disrupted in Schwann cells. Disruption of laminin γ1 gene expression resulted in depletion of all other laminin chains known to be expressed in Schwann cells. Schwann cells lacking …

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