Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"lambda-repressor"”.
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Folding Thermodynamic and Kinetic Characterization of Small Model Proteins: Lambda Repressor, U1A, Trpzip2 and PAO -12
Complete prediction of the folding processes for complex protein molecules through first principles is currently not possible (2003). Here we take an empirical approach towards a better understanding of the protein-folding problem, through thermodynamic and kinetic characterizations of several …
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Temperature- and pressure-induced protein dynamics from microseconds to minutes
… mechanism of folding of a model protein called lambda-repressor fragment 6-85. Specifically, Chapter 2 describes an effort to identify the rate-limiting step of lambda-repressor folding, Chapter 3 discusses potential origins of the slow (millisecond) phase in the folding of some lambda-repressor …
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Studies of Protein Folding on Membranes and in Crowded Environments and Bridging the Research-Teaching Gap in K-12 Science
… volume on the stability and kinetics of a stable Lambda Repressor mutant Y22WQ33YA3749G. Finally, I discuss two education projects that aim to bridge the gap between scientific research and K-12 teaching.
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Studies of protein folding on membranes and in crowded environments and bridging the research-teaching gap in K-12 science
… volume on the stability and kinetics of a stable Lambda Repressor mutant Y22WQ33YA3749G. Finally, I discuss two education projects that aim to bridge the gap between scientific research and K-12 teaching.
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Exploring Downhill Protein Folding Free Energy Landscapes
… propensity. A designed histidine containing lambda repressor mutant is identified to be a downhill folder even at its melting temperature, showing both thermodynamic and kinetic signatures of downhill folding for the first time. All the reported downhill folders are classified based on their …
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Computational investigations of protein dynamics and its implications for biological functions
… diseases. A fast-folding five-helix bundle λ-repressor fragment is chosen as a model system. A length of 80 amino acid residues puts it on the large end among all known microsecond folders and its size poses a computational challenge for MD studies. We simulate the folding of a novel …