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Showing 1 to 20 of 61 for “"lactoferrin"”.
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Wirkung von Lactoferrin auf den Organismus neonataler Hundewelpen
Die Wirkung der prebiotisch wirksamen Substanz Lactoferrin wurde an neonatalen Hundewelpen getestet. Diese wurden am 3. Lebenstag von der Mutter getrennt, in eine Kontroll- bzw. 4 Lactoferringruppen mit unterschiedlichen Dosierungen eingeteilt und mutterlos mittels Milchaustauscher aufgezogen. Es …
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Lactoferrin Supplementation to Holstein Calves During the Preweaning and Postweaning Phases
… were used to examine the effects of supplemental lactoferrin on feed intake, growth, and health during the preweaning and postweaning periods. One of three levels of lactoferrin was added to whole milk in order to produce three dietary treatments: 1.) 0 g⁄d, 2.) 0.5 g⁄d, 3.) 1 g⁄d. Milk (3.8 L⁄d) …
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Role of the lactoferrin-binding protein in pathogenesis of streptococcus uberis
… produces a surface protein capable of binding lactoferrin (Lbp), originally identified as an M-like streptococcal protein. We hypothesized that Lbp may play a role as a virulence factor. Structural similarity and amino acid sequence homology of Lbp to Mrelated proteins of Group A streptococci …
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Structural Characterization of Donkey Lactoferrin: Amino Acid Sequence and Glycan Compositions
Lactoferrin, a protein showing an array of biochemical properties, including immuno-modulation, iron-binding ability, as well as antioxidant, antibacterial and antiviral activities, was isolated from donkey milk by ion exchange chromatography.The characterization of its primary structure, by means …
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Effect of Lactoferrin to Increase Drug Permeability of Primary Pulmonary Mycobacterial Granulomas
… altering the immunopathology of granulomas using lactoferrin, an immunomodulating agent, it will allow greater penetration of therapeutics into the site of focal inflammation. Our lab has reported that oral bovine lactoferrin treatments during the innate immune response leads to significant …
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β-lactoglobulin and lactoferrin complex coacervates: Characterization and putative applications as encapsulation device
… coacervation between β-lactoglobulin (β-LG) and lactoferrin (LF) in the absence and presence of small ligands. The conditions of optimal β-LG - LF coacervation were found at pH range 5.4-6 with a molar excess of β-LG. Remarkably, LF showed selective coacervation with β-LG A, the slightly more …
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Supporting bone regeneration: Evaluation of endocrine peptides and delivery systems for local application of lactoferrin
… the optimal delivery of the bone anabolic factor lactoferrin (LF). Methods We developed an ex vivo osteocyte culture system, and investigated the effects of irisin and orexin on bone cells at different stages of development in vitro: on bone marrow stromal cells, osteoblasts, osteocytes, and …
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Development and evaluation of a beta-glucan biopolymer formulation of lactoferrin produced using a novel cryomilling technique
… to produce microparticles encapsulating bovine lactoferrin (bLF), a whey protein from milk. β-glucan was investigated as a protein delivery candidate for the first time in this study, the formulation demonstrated a significant improvement in in vivo activity, which suggested improved …
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The bovine lactoferrin gene : defining the minimal promotor region : a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry
Lactoferrin is an 80 kDa glycoprotein with two lobes, each of which bind a single iron atom. Originally isolated from milk, lactoferrin has since been identified in a variety of exocrine secretions and in the secretory granules of neutrophils. A number of functions have been proposed for …
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Estrogen Response Element and the Promoter Context of the Human and Mouse Lactoferrin Genes Influence Estrogen Receptor alpha-Mediated Transactivation Activity in Mammary Gland Cells
… estrogen responses of the human and mouse lactoferrin estrogen response element (ERE) in the context of their natural promoters. This research utilized molecular biology techniques to evaluate gene activation. Transfections of MCF-7 cells showed that liganded ER-alpha activates …
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Effect of bovine lactoferrin on T cell and NK cell populations and NK cell cytotoxicity in neonatal piglets
Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Seth Robbins (srobbins@illinois.edu) on 2013-08-30T16:47:06Z Item is restricted until 2015-08-30T16:47:05Z
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Immune Modulation of The Mycobacterium Tuberculosis Granulomatous Response
… were next performed to determine the ability of lactoferrin to modulate the immune response and pathology to mycobacterial cord factor. Lactoferrin is an iron-binding glycoprotein with immunomodulatory properties that decrease tissue damage and promote Th1 responses. Mice challenged with TDM and …
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Novel non-viral delivery systems for cancer gene therapy
… of targeting ligands such as transferrin and lactoferrin is an attractive tool to improve specificity and cellular uptake of carriers, and surface modification of dendrimers with hydrophilic polymers such as polyethylene glycol should facilitate lower systemic toxicity and promote the enhanced …
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Effect of bovine lactoferrin on T lymphocyte cell phenotype and function and the response to vaccination in the neonatal piglet
… positive effects for infant immune maturation. Lactoferrin (Lf), an iron binding glycoprotein found in breastmilk has been shown to have numerous physiological and immune properties that are nutritionally advantageous for infants. The goal of this thesis research was to discover how early …
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Lactoferrin in neonatal development: effects on intestinal structure and intestinal function and immune response in a piglet model of systemic Staphylococcus aureus infection
… (Kainonen et al 2013; Jacobi and Odle, 2012). Lactoferrin (Lf), a bioactive protein found in high concentrations in human milk, when fed orally, has bacteriostatic activity against S. aureus in vivo (Bhimani et al 1999) and has been proven efficacious against neonatal septicemia when …
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Exploring Metallic Flavor Perception: Analysis of Human Salivary Proteins and the Use of the Iron-Binding Protein Lactoferrin in Reducing Metallic Off-Flavors
… were studied. Metal chelators included lactoferrin (1 ?M), a natural metal-binding protein in milk and saliva, and EDTA (36 ?M), a synthetic chelator. Time-intensity (TI) evaluation (n=6, 4 female; age 40-70) of lingering metallic flavor indicated that metallic flavor decreased with a …
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Einfluss probiotischer Substanzen auf den antioxidativen Status von neugeborenen Hundewelpen
… wurde untersucht, ob die Zufütterung von Lactoferrin bzw. Enterococcus faecium einen Einfluss auf den antioxidativen Status der Tiere ausübt. Dazu wurden 42 neonatale Beagle-Welpen am 3. Tag nach der Geburt von den Muttertieren getrennt und in zwei unabhängigen Fütterungsversuchen von Hand …
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