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Showing 1 to 3 of 3 for “"lactate dehydrogenase A (LDH-A)"”.

  1. Development and Mechanistic Characterization of Novel Small Molecules as Cancer Therapeutics

    … of action to known agents. The development of lactate dehydrogenase-A (LDH-A) inhibitors as a novel anticancer strategy is discussed in Chapter 5. In Chapter 6, the mode of action of anti-cancer quinones is described. And finally, the discovery of triazole-containing small molecules as …

    uiuc Repository record for Development and Mechanistic Characterization of Novel Small Molecules as Cancer Therapeutics (opens in a new tab)

  2. Novel Functions of Cetuximab In Egfr-Targeted Therapy: Radiosensitization, Glycolysis Inhibition, and Cellular Redox Status Regulation

    … of cetuximab and radiation, while targeting lactate dehydrogenase A (LDH-A) restores the role of cetuximab in cell cycle arrest in cetuximab-resistant cancer cells. Moreover, targeting pyruvate dehydrogenase kinase 1 (PDK1), in combination with cetuximab, leads to a synergetic and synthetic …

    uthsc Repository record for Novel Functions of Cetuximab In Egfr-Targeted Therapy: Radiosensitization, Glycolysis Inhibition, and Cellular Redox Status Regulation (opens in a new tab)

  3. Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy

    Embargo set by: Seth Robbins for item 73141 Lift date: 2017-01-21T19:56:18Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system

    uiuc Repository record for Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy (opens in a new tab)