Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 46 for “"lactate dehydrogenase (LDH)"”.
-
The effects of whole pureed mango intake on serum biomarkers of muscle damage in response to moderate intensity aerobic exercise in sedentary adults
… treatment. There was a significant difference in Lactate Dehydrogenase (LDH) within the placebo group and in Myoglobin (MG) and cycling time at given wattage within both groups. There were no significant differences between treatment groups. Although not significant, there was a trend of reduced …
-
The metabolic profile of cardiac and skeletal muscle tissue from captive emus (Dromaius novaehollandiae) raised in northern Colorado: implications for assessing muscle health for emus with splayed-leg disorder
… µmol min-1 g-1 wet tissue), β-hydroxyacyl CoA dehydrogenase (HAD 78.9 ± 3.6 µmol min-1 g-1 wet tissue), and lactate dehydrogenase (LDH 239.5 ± 8.9 µmol min-1 g-1 wet tissue) of domesticated emu cardiac tissue. Emus had ~22% higher myoglobin levels in cardiac tissue compared to domesticated …
-
Hemocompatibility of polymeric materials for blood-contacting applications
… The cytotoxicity was investigated using lactate dehydrogenase (LDH) assay. The adsorption of key blood serum proteins was evaluated using micro-bicinchoninic acid (micro-BCA) assay. The results were visualized using SEM. Platelet adhesion and activation was investigated using live cell …
-
Chronic effects of single intra-peritoneal injection of endosulfan on rainbow trout (Oncorhynchus mykiss) and field observations of caged rainbow in Oshawa Creek
… (EROD), citrate synthase (CS), lactate dehydrogenase (LDH), and brain acetylcholine esterase (AChE) (caged fish only) enzymatic activities were measured. Trout injected with endosulfan experienced an increase of the anaerobic (LDH activity) and a decrease of the aerobic (CS …
-
Determining the mechanism of dichloroacetate-regulated processing of the Alzheimer’s disease-related amyloid precursor protein
… Hence, through manipulating pH, p53 levels, lactate dehydrogenase (LDH) activity, pyruvate and lactate levels, mitochondrial autophagy and oxidative stress, we aimed to investigate each potential mechanism by characterising the resultant effects on APP expression and proteolysis. Furthermore, …
-
Antibacterial Activities of Cannabidiol Against Two Major Oral Pathogens
… growth, as well as, biofilm metabolic activity, lactate dehydrogenase (LDH) activity, and extracellular polysaccharides (EPS) production. In the presence of nicotine, which upregulates biofilm formation, CBD demonstrated the same inhibitory effects on S. mutans growth and activities. CBD …
-
Regulation of mitochondrial respiration by LDHB suppression in hepatoma cell lines
… glycolysis, continuous generation of NAD+ by lactate dehydrogenase (LDH) with conversion of pyruvate to lactate is essential. Functional LDH is homo- or heterotetramers assembled from two types of subunit with LDHA and LDHB gene product. Recently, we reported that LDH5 isoenzyme formed by LDHB …
-
Antibody phage-displayed libraries derived from chicken immunoglobulin genes : a source of highly specific diagnostic antibodies
… a mixture of Plasmodium falciparum recombinant lactate dehydrogenase (LDH), histidine rich protein II (HRPII) and aldolase (ALDO), recombinant trypanosome variable surface glycoprotein (VSG) and malignant catarrhal fever virus (MCFV) each chicken produced egg yolk antibodies (IgY) against four …
-
A toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoids
… serum creatinine phosphokinase (CPK) and serum lactate dehydrogenase (LDH) levels (indicators of muscle damage) in view of the published reports of elevated levels in psychotic patients.
-
Determining the Usefulness of Aerobic and Anaerobic Enzyme Assays as Proxies for Rockfish Ecological Data.
… using metabolic enzyme assays. Enzymes used were lactate dehydrogenase (LDH), malate dehydrogenase (MDH), pyruvate kinase (PK), and citrate synthase (CS). Some muscle composition data (percent water, percent protein, percent lipid, and protein as a percentage of wet mass) were also used to help …
-
The Cost of Capturing Prey: Measuring Largemouth Bass Foraging Activity Using Glycolytic Enzymes (Lactate Dehydrogenase)
… of glycolytic (anaerobic) enzymes such as lactate dehydrogenase (LDH), in the axial, white musculature of fish. To examine the effect of prey size on anaerobic activity, I conducted a series of laboratory feeding trials with largemouth bass (Micropterus salmoides) predators (240-303 mm …
-
Identifying Metabolic Liabilities in Hürthle Cell Thyroid Carcinoma
… consumption of glucose and secretion of lactate, even in the presence of oxygen. Although many tumors exhibit increased glycolytic activity, most forms of cancer rely on mitochondrial respiration for tumor growth. Hürthle cell carcinoma of the thyroid (HTC) represents an outlier wherein …
-
Evolution Of Lactate Dehydrogenase Genes In Primates, With Special Consideration Of Nucleotide Organization In Mammalian Promoters
… may have occurred is through greater use of lactate as a neuronal fuel. Both the production of lactate, and conversion to pyruvate for use in aerobic metabolism, are catalyzed, in part, by the tetrameric enzyme lactate dehydrogenase (LDH). The two primary LDH genes, LDHA and LDHB, confer …
-
Integrated Analysis of Molecular and Clinical Features in Melanoma Patients with Brain Metastases
… performance score (KPS), elevated serum lactate dehydrogenase (LDH), the presence of extracranial metastases (ECMs), and uncontrolled (versus controlled) ECMs as clinical predictors of shorter survival. Multivariate analyses were performed with significant clinical factors and immune …
-
Effect of Oxygen-Limiting Tidal Conditions on Muscle Metabolism and Structure in the Giant Acorn Barnacle, Balanus nubilus
… to determine citrate synthase (CS) activity, lactate dehydrogenase (LDH) activity, and D-lactate levels. We also prepared a subset of SA and TD muscles from the chronic barnacles for histological analysis of fiber diameter (Feret’s), cross-sectional area (CSA), mitochondrial distribution and …
-
Desempenho atlético de cavalos de vaquejada: parâmetros fisiológicos, bioquímicos e hematológicos
… aminotransferase (AST), creatine kinase (CK), lactate dehydrogenase (LDH), albumin, total plasma protein, hematocrit, leukocytes, calcium, phosphorus and magnesium were determined. The experimental design was in randomized blocks; The animals were the blocks and the treatments were the moments …
-
Investigating the impact of e-cigarettes on lung cells: a combined in vitro and computational study
… transepithelial electrical resistance (TEER), lactate dehydrogenase (LDH) release, IL-8 secretion, and gene expression. Nicotine salt and flavoured aerosols significantly reduced TEER, increased LDH and IL-8 levels, and downregulated OCLN, TJP1, SCNN1A, ATP1A1, AQP3, and CHRNA5, indicating …
-
유전자 적중법을 이용한 조건적 LDHB 유전자 삭제 마우스 제작
… have altered glycolytic(glucose) metabolism. The lactate released by this altered glycolytic metabolism exported out of cancer cells. Because the tumor environment is highly hypoxic so that cancer cells produce of ATP by glycolysis. Cancer cells uptake glucose much more than normal cells. Because, …
-
Characterisation of two desiccation-linked dehydrins from Xerophyta humilis
… investigated using citrate synthase (CS) and lactate dehydrogenase (LDH). The preservation of enzyme activity was observed in both CS and LDH. This preservation of enzyme activity was further maintained by the presence of trehalose. Anti-aggregation roles were also investigated, however, …
-
GC-MS Investigation of Metabolic Activity in 4-Hydroxy-2-Oxoglutarate Aldolase Deficiency of Primary Hyperoxaluria Type 3
… which is formed from oxidation of glyoxylate by lactate dehydrogenase (LDH) and which readily crystallizes as calcium oxalate in renal tissue. PH3 is the most recently characterized of the variants of PH, and it is also the least understood. PH3 is caused by a malfunction in the enzyme …
Page 1 of 3