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Showing 1 to 20 of 136 for “"lactate dehydrogenase"”.
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Rat Liver Lactate Dehydrogenase: Mechanism and Specificity Studies
Made available in DSpace on 2014-12-09T17:34:57Z (GMT). No. of bitstreams: 1 6500771.pdf: 2299837 bytes, checksum: 9d52e5006b237b3344e6c1874b80b08d (MD5) Previous issue date: 1964
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Production of Monoclonal Antibodies for Toxoplasma gondii Lactate Dehydrogenase
… kit that has high sensitivity against LDH (lactate dehydrogenase) of T. gondii, at the first of all, hybridoma cell lines producing monoclonal antibodies with high affinity and specificity against T. gondii LDH (TgLDH) were established. Methods: After 6-8 week old BALB/c mice were immunized …
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Human lactate dehydrogenase heterogeneous biocatalyst for efficient anticancer drug screening
L'abstract è presente nell'allegato / the abstract is in the attachment
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A Biochemical Study of Gossypol and Lactate Dehydrogenase X Binary Interactions
… interaction with native and trypsin digested lactate dehydrogenase-X (LD-X), a sperm-specific isozyme, and (b) its binding in vitro in primary cultures of spermatogenic cells. Mouse LD-X was cleaved with trypsin before and after treatment with gossypol. This was followed by high performance …
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Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy
Embargo set by: Seth Robbins for item 73141 Lift date: 2017-01-21T19:56:18Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system
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Protection Mechanisms of Excipients on Lactate Dehydrogenase during Freeze-Thawing and Lyophilization
… of excipients on a labile model protein, lactate dehydrogenase (LDH), during freeze-thawing and lyophilization. Cryoprotectants are excipients that protect labile molecules during freezing. Some investigators believe that preferential exclusion is the predominant mechanism to explain the …
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Pressure Dissociation and Temperature Stability of Lactate Dehydrogenase (Oligomeric, Proteins, Conformational, Drift, Activity)
The deactivation of lactate dehydrogenase by pressure and its subsequent reactivation have been studied by Jaenicke et al. Although they did not carry out direct measurements of the molecular size they ascribe the slow reactivation at atmospheric pressure to the reassociation of the separated …
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Investigation of the cancer testis antigen lactate dehydrogenase C as a CD8 T cell target
… of HGSC cases, the cancer testis (CT) antigen lactate dehydrogenase C (LDHC) is expressed in 76% of tumours (22/29). As LDHC presents with tumour specificity in women, I hypothesize that LDHC is an immunogenic target in HGSC patients, and that LDHC-specific T cells can be activated and expanded …
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The Cost of Capturing Prey: Measuring Largemouth Bass Foraging Activity Using Glycolytic Enzymes (Lactate Dehydrogenase)
… of glycolytic (anaerobic) enzymes such as lactate dehydrogenase (LDH), in the axial, white musculature of fish. To examine the effect of prey size on anaerobic activity, I conducted a series of laboratory feeding trials with largemouth bass (Micropterus salmoides) predators (240-303 mm …
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Evolution Of Lactate Dehydrogenase Genes In Primates, With Special Consideration Of Nucleotide Organization In Mammalian Promoters
… may have occurred is through greater use of lactate as a neuronal fuel. Both the production of lactate, and conversion to pyruvate for use in aerobic metabolism, are catalyzed, in part, by the tetrameric enzyme lactate dehydrogenase (LDH). The two primary LDH genes, LDHA and LDHB, confer …
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Mast Cell Histamine Release Induced by Portuguese Man-of-War (Physalia) Venom
… for both released histamine and released lactate dehydrogenase, a cytoplasmic enzyme marker.</p> <p>Physalia venom causes the release of both histamine and lactate dehydrogenase. The release of histamine is dose-dependent and approaches 100% at high doses of venom. The dose-response curve …
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The Evolution of Gene Expression in The Umbrid Fishes: A Comparison of Phylogenies Based Upon Inferred Differences in Structural and Regulatory Genes (Lactate Dehydrogenase, Duplicate, Controller Nodes, Esocidae, Salmoniformes)
Genetic distances, based on differences in 51 protein coding structural genes, established relative divergence times among species of mudminnows (Umbridae) and Esox (Esocidae), within the order Salmoniformes. Both cladistic and phenetic analyses support: (1) a close relationship of Umbra limi and …
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Studies on pyridine nucleotide-dependent processes in Haemophilus influenzae
… nucleotide pyrophosphatase. A cytosolic lactate dehydrogenase, specific for D(-)-lactate was purified to electrophoretic homogeneity 2100-fold with a 14% yield. The purified enzyme was demonstrated to be a tetramer of M, = 135,000. It catalyzes essentially the reduction of pyruvate with …
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Signal transduction pathways involved in skeletal muscle fibre type regulation
… cyclosporin A failed to prevent a decrease in lactate dehydrogenase activity and an increase in NADH-TR staining intensity, both characteristics of a transition towards a slower phenotype, following CLFS of the fast rat tibialis anterior muscle. Blockade of the ERKI/2 pathway in primary …
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Desempenho atlético de cavalos de vaquejada: parâmetros fisiológicos, bioquímicos e hematológicos
… aminotransferase (AST), creatine kinase (CK), lactate dehydrogenase (LDH), albumin, total plasma protein, hematocrit, leukocytes, calcium, phosphorus and magnesium were determined. The experimental design was in randomized blocks; The animals were the blocks and the treatments were the moments …
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Colonocyte-Derived Lactate Promotes Enterobacteriaceae Fitness During Non-Infectious Colitis
… metagenomics, we observed that microbial lactate utilization is elevated during non-infectious chemically-induced colitis. We recapitulated these findings in a genetic model of colitis and found that lactate utilization via the respiratory lactate dehydrogenase LldD enhanced E. coli …
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STUDYING THE INTERACTION OF NANO- & MICROPLASTICS WITH ENTEROVIRUS AND THEIR CYTOTOXICITY ON HUMAN LUNG CELL LINE
… and inheritance across 11 generations. Elevated lactate dehydrogenase levels and increased apoptosis indicated persistent intracellular accumulation and compromised cellular health.
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Influence of selection for breast muscle mass on pH and metabolism of supracoracoideus muscle from male and female turkey
… lower average pH (6.68; p < 0.0001), and greater Lactate Dehydrogenase (293 mmol NADH min-1mug-1 ; p < 0.0001) and Glyceraldehyde Phosphate Dehydrogenase (0.4452 mmol NADH min-1mug-1; p < 0.05) activities than the HM and FL lines. The LM line had the highest ratio (2.33:1) (p < 0.05) of adult to …
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The effects of whole pureed mango intake on serum biomarkers of muscle damage in response to moderate intensity aerobic exercise in sedentary adults
… treatment. There was a significant difference in Lactate Dehydrogenase (LDH) within the placebo group and in Myoglobin (MG) and cycling time at given wattage within both groups. There were no significant differences between treatment groups. Although not significant, there was a trend of reduced …
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