Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 85 for “"laboratory medicine"”.
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Experiences of biomedical sciences students and staff in blended learning during the COVID-19 pandemic lockdown in a University of Technology, Durban, KwaZulu-Natal
… requirements for the Master’s Degree in Medical Laboratory Medicine, Durban University of Technology, Durban, South Africa, 2025.
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A study of the use of immunohistochemical stains in an academic hospital
… those measures have not been developed for laboratory medicine. This study examines how the pathology department at Massachusetts General Hospital approached this challenge. Specifically, the study is focused on the use of immunohistochemical (IHC) stains in the pathology department. This …
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Contemporary Models, New Approaches and Perspectives in Training Students of the Medical Laboratory Technician Speciality // Съвременни модели, нови подходи и перспективи в обучението на студентите от специалност „Медицински лаборант
The dynamic development of laboratory medicine requires a shift in student motivation, consistent with their competitiveness on the European and other markets. The thesis aims to analyse the specific features, new approaches in training and perspectives of medical laboratory technicians and their …
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Validation of an adjusted calcium formula using the Roche calcium (NMBATPA) and albumin (BCG) methods at Groote Schuur Hospital
… by the Association for Clinical Biochemistry and Laboratory Medicine (ACB) advocate that laboratories should use formulae specific for their tCa and albumin methods and analytical platforms. The National Health Laboratory Service at Groote Schuur Hospital (GSH) undertook to investigate this …
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Determination of reference intervals and decision limits for thyroid stimulating hormone and thyroxine on cord blood samples
… European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) total allowable error goals for TSH, with RIA results showing a small positive bias. Conclusion: This study establishes reference intervals for cord blood TSH and FT4 in a South African context. Cord blood presents …
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The clinical value of genetic analyses of bone and soft tissue tumors
Tumors of bone and soft tissue are common but only constitute 1 % of all malignant tumors. The malignant tumors are often difficult to diagnose due to their rarity and morphological resemblance between subtypes. This makes the diagnostic process challenging. Thus, there is a need for ancillary …
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Pseudovirions in the Study of Papilloma- and Polyomaviruses
The papilloma- and polyomaviruses are small DNA viruses that infect humans. Some members of these virus families can cause cancer in experimental animals and some are also established as carcinogenic to humans. Detection of specific antibodies to these viruses allows tracking past and present …
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Human milk as a source of tumor killing molecules. From MAL to HAMLET.
HAMLET (Human alphalactalbumin made lethal to tumor cells), a complex between the partially unfolded alphalactalbumin and oleic acid, was discovered by serendipity when anti-adhesive properties of human milk were examined. HAMLET kills tumor cells but not healthy differentiated cells. Native …
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Decoding mucosal immunity: Impact of SARS-CoV-2 and Bordetella pertussis vaccination and infection
Contains fulltext : 319744.pdf (Publisher’s version ) (Open Access)
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Gestational trophoblastic disease - clinical prediction and exploration of the immune cell landscape
Contains fulltext : 292282.pdf (Publisher’s version ) (Open Access)
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The Role of Inflammatory Lipid Mediators on Colon Cancer Initiating Cells (CICs)
Colorectal cancer (CRC) is one of the major causes of cancer globally. Recent studies proposed a role for cancer initiating cells (CICs), a small subset of replication-competent cells, in colon carcinogenesis. Although the role of inflammatory lipid-mediators in CRC progression is well known, their …
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Novel Cutaneous Human Papillomaviruses and Biomarkers in the Skin Lesions
Non-melanoma skin cancer (NMSC), comprising of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), is the most prevalent cancer amongst Caucasians. The main risk factor for the development of NMSC is UV-irradiation but human papillo-mavirus (HPV) might be a co-factor. We extended the …
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Characterisation of weak and null phenotypes in the KEL and JK blood group systems
The focus of this thesis is on KEL and JK, two clinically important blood group systems, and the investigations of blood samples with aberrant antigen expression as in null and weak phenotypes, or with a phenotype that does not correspond to genotype. With the increasing use of DNA assays based on …
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The Columnar Lined Esophagus: aspects on the assessment of dysplasia and on the relationship with the esophageal submucosal glands
Columnar metaplasia, where columnar epithelium replaces the normal squamous epithelium in esophagus, is considered to be a precancerous condition in which the development of adenocarcinoma can be followed through various grades of dysplasia. The interpretation of these histological changes is …
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The regulation of blood coagulation by high-density lipoprotein particles
High-density lipoprotein (HDL) has anti-atherogenic properties and the plasma level of HDL cholesterol correlates inversely with the risk of coronary artery disease. The atheroprotective functions of HDL can be explained by its function in the reverse cholesterol transport. Blood coagulation is …
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Signalling and trafficking of the cysteinyl leukotriene receptors in intestinal epithelial cells
Inflammation is a response to injury or pathogen invasion. A large proportion of the bodie's immune system is centred in the gastrointestinal tract (GI). Prolonged inflammatory conditions of the GI have been suggested to increase the risk for developing colon cancer. The cysteinyl leukotrienes …
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Functional properties of galectin-3. Beyond the sugar binding.
Contemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in …
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Studies on renal progenitor cells and kidney cancer
Kidney cancer and renal injuries affect millions of people in the world resulting in high patient morbidity and mortality, as well as one of the most extensive medical costs for society. Upon renal injury the kidney has an endogenous ability to repair damaged tubules and restore kidney function, …
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Phosphorylation of ERα and HIF-1α in breast cancer with focus on tamoxifen response and links to kinase activation
Anti-oestrogens are commonly used in adjuvant breast cancer treatment and for a long time tamoxifen has been the main endocrine treatment. Patients who are eligibly for endocrine treatment are selected by the tumour-specific expression of oestrogen receptor (ER) and approximately 70 % of all breast …
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Physiological recovery from night-call duty - a field study of physicians
Abstract Physicians’ work on night-call entails long and stressful working hours with high demands and disrupted sleep. Incomplete recovery is considered to be the most important link between acute physiological stress reactions, shift work and chronic health effects. Mental and physiological …
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