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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 340 for “"label free"”.
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External cavity laser label-free biosensor
… cavity laser, we demonstrate a new type of label-free optical biosensor that achieves a high quality factor through the process of stimulated emission, while at the same time providing high sensitivity, large dynamic range and simple detection instrumentation. The photonic crystal is …
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Numerical characterisation of label free optical biosensors
… thesis to characterize, analyse and optimise label-free optical biosensors for the detection of micron size biological objects like bacteria such as E.coli and nanometre size biomolecules such as antibody, nucleic acids and proteins. These sensors are all suitable for deep-probe sensing as …
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Label-free optical imaging of neural activity
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01
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Label-Free Functional Imaging Of Platelets At Nanoscale
… is unsuitable for genetic manipulation, platelet labelling is often conducted using membrane markers or with fixed samples which could restrict nanoscopic imaging of the platelet dynamics at video rate. Rapid assessment of platelet dysfunction without markers will accelerate many aspects of …
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Label-Free Functional Imaging Of Platelets At Nanoscale
… is unsuitable for genetic manipulation, platelet labelling is often conducted using membrane markers or with fixed samples which could restrict nanoscopic imaging of the platelet dynamics at video rate. Rapid assessment of platelet dysfunction without markers will accelerate many aspects of …
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Photonic Crystal Enhanced-Fluorescence and Label -Free Bioimaging
… is outlined for predicting photonic crystal label-free imaging resolution based on resonance spectral characteristics. Devices are characterized by patterning a resolution standard onto the sensor using photolithography, and excellent design control over label-free imaging resolution is …
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External cavity laser biosensor for label-free detection
Optical label-free biosensors serve as a powerful detection tool to analyze biomolecular interactions, and have been widely used in pharmaceutical drug discovery and biochemical sensing. Desirable performance metrics for such sensors include high sensitivity and fine resolution, which are essential …
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Label-free breast histopathology using quantitative phase imaging
… methods for automated diagnosis. A quantitative, label-free and automatable microscopic modality for breast cancer diagnosis is, thus, needed to address these shortcomings in the standard method. Furthermore, prognostic biomarkers are important tools used by clinicians in order assess the disease …
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Affinity Flow Fractionation for label-free cell sorting
Capture and isolation of flowing cells from body fluids such as peripheral blood, bone marrow or pleural effusion has enormous implications in diagnosis, disease monitoring, and drug testing. However, in many situations the conventional methods of cell sorting are of limited use due to complex …
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Adaptive Fiber Source for Label-free Nonlinear Microscopy
Nonlinear microscopy enables label-free visualization of biological processes in live samples at sub-cellular spatial resolution and sub-millimeter penetration depth, enabling the in-vivo study of mechanisms underlying several cellular functions. Due to the low absorption cross-section of the …
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A label-free, fluorescence based assay for microarray
… of unknown sequence, called targets, which are labeled with fluorescent dyes. Due to specific molecular recognition among the base pairs in the DNA, the binding or hybridization occurs only when the probe and target sequences are complementary. The nucleotide sequence of the target is determined …
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Automatic Label-Free system for cell viability on-a-chip [Sistema automatico Label-Free per la determinazione della vitalità cellulare su chip]
… significativo verso il monitoraggio automatico, label-free e in tempo reale della vitalità cellulare all’interno di chip microfluidici. Combinando idrodinamica, ottica, intelligenza artificiale e soluzioni portatili a basso costo, questo lavoro getta le basi per la prossima generazione di …
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Label-free tracking of photocatalysis on a single nanoparticle
… advancement in this work was the use of isotope labeling in the single-molecule-level sensitive nanoscale probing of a NP surface. This, in turn allowed the confirmation that detected surface species are the intermediates and products of the catalytic reaction—CO2RR—rather than spurious …
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Benchmarking methods for label-free quantitative proteomics data analysis
… protein quantification. In particular, MS-based label-free quantification (LFQ) proteomics can quantify thousands of proteins in complex biological samples. However, the molecular heterogeneity of such samples and the technological limitations of MS-based proteomics pose inferential challenges, …
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Label-free buoyant mass assays with suspended microchannel resonators
… of new assay formats based on microfluidic, label-free platforms enable radical reductions in assay complexity and reagent requirements with the potential for such applications. Suspended microchannel resonators (SMRs) are highly sensitive, batch-fabricated microcantilevers with embedded …
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Carbon nanotube-based sensors for label-free protein detection
… (hGH-R), with potential use as a real-time and label-free measurement of protein activity. Native hGH is detected in the micromolar range, and an invariant equilibrium dissociation constant of 9 uM is revealed upon fitting the calibration curve to a single-site adsorption model. Selective …
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Development of label-free colorimetric plasmonic biosensor for biomedical applications
Item withdrawn by Laura Spradlin (lspradl2@illinois.edu) on 2014-05-13T18:52:16Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Hsiao_Austin.pdf: 5286551 bytes, checksum: 32405b56423ef1707cfe26ccf405fa40 (MD5)
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Development of label-free detection systems targeting food-borne pathogens
… develop the proof-of-concept methodology for a label-free immunoassay technique utilizing photonic crystal biosensors targeting bacteria, specifically E. coli O157:H7. In this project, it is shown that detergent-lysing of the cells and extraction of their membrane antigens allows for the …
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