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Showing 1 to 3 of 3 for “"kruppel-like factor 6"”.
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Characterization of Aryl Hydrocarbon receptor and Kruppel-Like-Factor-6 interaction
… (AhR) is a ligand activated transcription factor which regulates toxic response to environmental pollutants, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Upon ligand activation, the AhR translocates to the nucleus, dissociates from its chaperone complex, and dimerizes with the Aryl …
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Molecular Insights and Physiological Consequences of Aryl Hydrocarbon Receptor Regulated Plasminogen Activator Inhibitor-1 Expression
… receptor (AhR), a ligand-activated transcription factor, attenuates liver regeneration in vivo when activated by its prototypical agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) following 70% partial hepatectomy (PH). One reported target of the AhR that may account for suppression of the …
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Novel Roles of the Aryl Hydrocarbon Receptor in Normal Physiology and Epigenetic Reprogramming
… ligand activated, cytosolic transcription factor belonging to the basic Helix-loop-helix Per-ARNT-Sim superfamily of proteins. AhR has classically been associated with environmental toxicology owing to the fact it mediates the toxic effects of halogenated aromatic hydrocarbons and …