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Showing 1 to 2 of 2 for “"kinetic discrimination"”.
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Photonic resonator absorption microscopy for biosensing with digital resolution
… at a very low concentration and with single-base discrimination without the need for sophisticated equipment, large volumes, or elaborate sample processing is a challenge. To address this, we present an approach that is highly specific for a target miRNA sequence and has the ability to provide …
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Bioanalytical applications of microfluidic devices
… single nucleotide polymorphisms (SNPs). SNP discrimination using alkaline dehybridization has long been neglected because the pH range in which thermodynamic discrimination can be done is quite narrow. We found, however, that SNPs can be discriminated by the kinetic differences exhibited in …