Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"killer immunoglobulin like receptor"”.
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The pattern and functional consequence of Killer Immunoglobulin-like Receptor expression on T cells.
Killer immunoglobulin-like receptors (KIRs) are a family of proteins expressed on human natural killer cells and a subset of T cells. Several inhibitory KIRs have been shown to recognise MHC class I molecules (predominantly HLA-C), with their engagement preventing target cell lysis. The ligand(s) …
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Prognostic markers associated with tyrosine kinase inhibitor treatment response and maintenance of treatment free remission in chronic myeloid leukaemia
… metric called the “doubling time”. A patient’s Killer Immunoglobulin-like Receptor (KIR) genotype is also correlated with survival as well as molecular outcomes. Whilst the biological basis for this interaction is poorly understand, it is believed to be underpinned by the innate immune system’s …
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Evaluation von KIR-Liganden Inkompatibilität bei unverwandten Knochenmark-/ Stammzelltransplantationen
We performed a retrospective study in 185 patients with myelogenous leukemias who had received hematopoietic cells from unrelated donors. The aim of this study was to answer the question wether the benefit of KIR ligand incompatibility seen in haploidentical tranplantations can also be seen using …