Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"kidney transplant recipients"”.
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Dopaminergic Genetic Contributions to Obesity in Kidney Transplant Recipients
<p><strong>Background:</strong> Kidney transplant recipients are a population who experience a high likelihood of gaining a significant amount of weight (between 6 and 13 kilograms) during the first year after transplantation. However, not all kidney transplant recipients gain weight. Studies have …
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Tuberculosis In paediatric kidney transplant recipients a single centre experience
… Tuberculosis remains a major challenge in transplantation particularly in endemic countries. The incidence, clinical manifestations, and optimal investigations for TB specifically in the paediatric post-transplant population have not yet been adequately studied. This study aims to describe …
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Genotypes and Clinical Characteristics of BK Virus in Kidney Transplant Recipients
… emerged as a major cause of allograft loss in kidney transplant recipients over the past decade. The presence of BK virus in urine or blood indicates reactivation of the virus not necessarily accompanied by BK virus associated nephropathy. BK virus genotypes have been described based on the DNA …
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Characterizing Dietary Intake and Physical Activity Affecting Weight Gain in Kidney Transplant Recipients
<p>Weight gain following kidney transplant is a significant problem with 50 to 90% of kidney transplant recipients gaining weight. Potential factors leading to weight gain following kidney transplantation have been thought to include a change in lifestyle such asdietary intake and physical …
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The relevance of performing 24-hour ambulatory blood pressure And pulse wave analysis in kidney transplant recipients
… but this is not routinely performed in kidney transplant units. This study was to determine if 24-hour ABPM, compared with office BP in kidney transplant recipients, would be more informative regarding BP management, and if pulse wave analysis (PWA) would assist in risk stratification. …
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Association of GLP-1 Receptor Agonist Use with Kidney and Cardiovascular Outcomes in Stable Kidney Transplant Recipients
… in reducing cardiovascular events and improving kidney function in patients with type 2 diabetes. Due to these hopeful improvements, kidney transplant recipients (KTRs) have started using GLP-1RA. However, their effects in KTRs remain largely unstudied in clinical studies. This thesis uses a …
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Sleep Disorders and Kidney Transplant Outcomes: Findings From an 18-Year (1997-2015) Historical Cohort Study
<p>A historic cohort study of kidney transplant recipients with a failed graft was conducted to examine the associations between sleep disorders and kidney transplant outcomes. Adult kidney transplant recipients who were transplanted and failed or died with a functioning graft during the designated …
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Time-Related Centile Ranges for Quality of Life Outcomes in Renal Transplantation
… and monitoring quality of life (QoL) following kidney transplantation. QoL is commonly viewed as an important indicator of successful outcomes in chronic disease including kidney transplantation. Despite extensive research documenting the value of QoL, routine measurement of QoL outcomes in …
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Increasing Transplant Medication Knowledge Through Implementation Of A Medication Education Intervention Algorithm
… (LHL) has profound implications on measured transplant outcomes as it is associated with higher incidence of graft loss, organ rejection, decreased immunosuppression medication adherence, and increased hospital re-admissions. Identification of patients with limited health literacy allows for …
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An Analysis of the Differences in Preemptive Kidney Transplantation Between Blacks and Whites
… are inequities in the allocation of cadaver kidneys for preemptive kidney transplants (PKT) between blacks and whites.</p> <p> <strong>Methods. </strong>This analysis uses descriptive statistics and univariate and multivariate analyses to identify factors associated with the determination of …
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Development of a framework for multiomic analysis in disease research
… and transcriptomic analysis was conducted in kidney transplant recipients with a variety of rare and common primary renal diagnoses (n = 52) compared to controls with no evidence of kidney disease (n = 28), identifying novel (TTC21B and PLEKHA1) and previously known markers of kidney disease …
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A Mixed Methods Evaluation of Patient and Provider Perspectives of Chronic Illness Management Following Kidney Transplantation
… Inconsistent, fragmented care coordination in kidney transplant recipients (KTRs)—whose management requires long-term, complex care, and multiple handoffs among providers—has been shown to result in suboptimal care and higher costs. In order to move forward in improving long-term outcomes, it …
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Identificazione di profili di rischio cardiovascolare nel trapianto di rene: polimorfismi di geni coinvolti nei processi di infiammazione e di apoptosi
… the main cause of morbidity and mortality in kidney recipients. This study was undertaken to assess the impact of functional polymorphisms located in cytokine and apoptosis genes on CVD after kidney transplantation. Cytokine polymorphisms, generally located in gene regulatory regions, are …
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The incidence and impact of Human Papillomavirus in HIV infected transplant patients
… Human imunnodeficiency virus (HIV) positive transplant patients have two modes of immunosuppression - the disease itself and the additional immunosuppression required after transplantation, which intuitively places them at a higher risk for this type of infection, if compared to their HIV …
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Investigation of novel therapeutic strategies in B cell and antibody mediated disease
… in some autoimmune diseases and in solid organ transplantation. In addition to antibody generation, there is increasing interest in the antibody-independent functions of B cells, including their ability to regulate immune responses via the production of IL10. In this thesis I firstly explored …
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Characterisation of T cell responses to proteins expressed during Human Cytomegalovirus latency
… to latency-associated proteins were detected in kidney transplant recipients immediately following primary HCMV infection, there were no such IL-10 secreting sub-populations, despite IL-10 T cell responses being detected to two lytic proteins, US3 and pp71. Given that latency-specific IL-10 …
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HOT study: the development, management and results from phase IIB, randomised controlled trial of heme arginate in recipients of deceased donor renal transplants
… injury (IRI) that occurs during renal transplantation. IRI increases the likelihood of delayed graft function (DGF), which negatively impacts on the long-term survival of a transplanted kidney. One enzyme of interest, heme oxygenase-1 (HO-1), degrades heme and protects against the …