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Showing 1 to 18 of 18 for “"kidney stone disease"”.
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Probiotics for the management of kidney stone disease
Kidney stones contain various combinations of chemicals, however, 80% consist of calcium oxalate. Oxalate in humans is either absorbed into the urinary tract and excreted in urine or degraded by gut bacteria. Oxalate-degrading gut bacteria play a critical role in human oxalate homeostasis, …
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Evaluating oxalate-degrading Lactobacillus spp. for their ability to be used as probiotics in the treatment of kidney stone disease
Although the direct cause of kidney stone formation is not known, reports have suggested it is probably a multifactorial disease. Lactobacillus strains which potentially had increased ability to degrade oxalate were previously isolated from a healthy low kidney stone risk group. The aim of this …
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Urinary prothrombin fragment 1 : a potential role-player in the protection of South African blacks from calcium oxalate kidney stone disease
The incidence of kidney stones amongst South Africa's black population is rare. This is in contrast to the white population, whose stone rate is similar to that in Western society. Urine composition alone does not account for these differences. This thesis presents a study of the inhibitory role of …
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Investigation of the in vitro and in vivo effects of some herbal preparations on risk factors for calcium oxalate kidney stone disease
… Phyllanthus niruri, Orthosiphon stamineus and Cystone®) were investigated as potential therapeutic and prophylactic agents for kidney stone disease. These studies were executed in the context of the existence of a virtually stone-free (black) and a stone-prone (white) population group in South …
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Dietry and microbiological investigation in South African black and white subjects as a key to understanding the difference in the incidence of kidney stone disease in the two race groups
Kidney stones occur in the South African white population to the same extent as in other westem countries. However, the incidence of this disease in the South African black population is extremely rare. In this thesis, investigations were undertaken to establish whether different renal handling …
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Studies of genetic, gastrointestinal, renal and dietary factors in white and black South African subjects as a possible key to understanding the relative absence of calcium oxalate kidney stone disease in the black population
The incidence of urolithiasis in South Africa's black population is extremely rare «1%) while in the white population it is similar to that of western countries (-15%). The present thesis was aimed at shedding more light on the complex nature of the physicochemical, biochemical and physiological …
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Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation
… Western world are likely to suffer at least one kidney stone in their life. The incidence of kidney stone disease in South Africa is similar in white males; however stone occurrence in the South African black population is extremely rare. The difference between the incidences of kidney stones in …
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Inhibition of Calcium Oxalate Monohydrate Crystallization Using Organic Growth Modifiers
… (COM), the most common component in human kidney stone diseases, was investigated using various structural derivatives of citrate, a known inhibitor of COM crystallization. Bulk crystallization studies revealed the specific binding of modifiers to COM crystal surfaces. Kinetic studies were …
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Comparative Analysis of Kidney Stone Composition in Patients from Ghana and South Africa: Case Study of Kidney Stones from Accra and Cape Town
… of this study was to describe and compare the kidney stone composition of kidney stone patients receiving treatment at the Korle-Bu Teaching Hospital (KBTH), Accra (Ghana) and Groote Schuur Hospital (GSH), Cape Town (South Africa). Methods: The study was a retrospective folder review of …
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Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects
… However, in the black population, this disease is extremely rare. Differences in the gastrointestinal and renal handling of several lithogenic and antilithogenic agents in the two ethnic groups have been reported, but the rarity of kidney stone disease in the black group remains a …
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Deep Photoacoustic Imaging and Acoustic Cavitation Mapping in Shockwave Lithotripsy
<p>Kidney stone disease is a major health problem worldwide. Shockwave lithotripsy (SWL), which uses high-energy shockwave pulses to break up kidney stones, is extensively used in clinic. However, SWL can produce cavitation in vivo, and the rapid expansion and violent collapse of cavitation bubbles …
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Investigation of the role of dietary myo-inositol hexakisphosphate (phytate) on the relative risk of calcium oxalate kidney stone formation in black and white male South African subjects
… studies have shown that caJclum oxalate (CaOx) stone-formers have lower urinary concentrations of myo-inositol hexakisphosphate (phytate or IPe) than healthy individuals, that dietary intake of this substance leads to its increased urinary excretion and that it is an inhibitor of CaOx nucleation …
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Physical, chemical and biological controls on the origin, crystallization and dissolution of human kidney stones
Kidney stones are mineral deposits in the renal system that afflict 1 in 11 people worldwide and the incidence and prevalence is increasing globally. Over 70% of stones are composed of calcium oxalate and other mineralogies include struvite, brushite, and apatite. Currently, stones are thought to …
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Investigation of the effect of hydroxycitric acid on urinary calcium oxalate risk factors for kidney stone formation in artificial urine: theoretical modelling and in vitro crystallisation experiments
… or urolithiasis, commonly known as kidney stones, is a common medical problem. Kidney stones are composed of different mineral types. Calcium Oxalate is the most common kind of stone. The principal aim of this research was to establish whether hydroxycitrate (HCA) affects and/or …
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Mutationsspektrum in den Genen SLC3A1 und SLC7A9 bei jugendlichen Cystinuriepatienten
Cystinuria is a hereditary kidney stone disease which is caused by a renal tubular defect of reabsorption of cystine and the dibasic amino acids lysine, arginine and ornithine. Once the threshold of solubility is exceeded cystine precipitates and subsequently patients suffer from recurrent kidney …
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A contemporary model of presentation and evaluation of nephrolithiasis in children // Съвременен модел на презентация и оценка на нефролитиазата в детска възраст
Изборът на темата е обусловен от нарастващата честота на заболяването, разпространението му сред всички възрастови групи, ролята му за развитие на ХБЗ/ хронично бъбречно заболяване/, както и ендемичния му характер за България. Бъбречно – каменната болест сред педиатричната популация поставя редица …
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Rarity of kidney stones in South Africa's black population : studies of urinary macromolecules, crystal matrix extract containing osteopontin, and bone turnover markers in urine and serum from black and white subjects as a key to understanding this paradox
… factors contributing towards the rarity of kidney stone disease in the South African black population. Healthy, age-matched male subjects from the black and white population groups were recruited for this purpose. In several of the studies, subjects followed a standardized diet and were …